The use of cryo-techniques in macromolecular crystallography has increased enormously over the last eight years and has become a vital part of modern X-ray data-collection methods. This paper presents some reasons for the rise in popularity of cryo-techniques and a brief outline of the basic methods, followed by a detailed discussion of factors to be considered when trying to optimize both the ...

Eric S Underbakke and Laura L Kiessling The EMBO Journal (2010) 29, 4237. doi:10.1038/emboj.2010.303 Correction to: The EMBO Journal (2010) 29, 3435–3436. doi:10.1038/emboj.2010.246 Since the publication of this paper, the authors have noticed errors in reference citations. On page 3436, left column, rows 24 and 32, the reference citations for ‘Sourjik and Berg, 2004’ should instead refer to ‘N...

Journal of Hematology & Oncology is pleased to see the exponential growth in the number of publications from China, especially in hematology and oncology. This editorial calls for putting more weight on the quality of the future scientific output and invites rigorous dialogs among policy makers, granting agencies, academic leaders, physicians, and scientists, followed by concrete actions, to ac...

A game of simultaneous free entry and sequential output choices is analyzed. Firms enter simultaneously in stage 1 by paying a fixed cost, and they choose output levels sequentially in subsequent stages. At the subgame-perfect equilibrium of the game, the production level of a firm is decreasing with the order of the firm in the decision-making. The firm that is the last to choose output produc...