Radioactive DNA was prepared in extensive (4 h) Dane particle DNA polymerase reactions. In different experiments the amount of new DNA, determined by the amount of nucleotide incorporation into an acid-insoluble form, was between 29 and 45% of the total circular DNA isolated from Dane particle preparations after the reaction. DNA reassociation kinetics were used to determine the complexity of t...

Potegal (1972) proposed that the caudate nucleus was involved in processing sensory (especially vestibular) cues for egocentric spatial orientation. The purpose of these experiments was to determine the effect of caudate nucleus lesions on a return from passive transport (RPT) task, which has been shown to depend on vestibular input (Miller, Barnett, & Potegal, Note 1). In the first experiment,...

Recently, we reported that oxidative stress decreases D1 receptor numbers and G protein activation in renal proximal tubules (RPT), resulting in diminished natriuretic response to dopamine in old rats. We tested the hypothesis that exercise in old rats will decrease oxidative stress and restore natriuretic response to D1 receptor agonist, SKF 38393. Old (23 mo) rats were subjected to rest (sede...

We compared the characteristics of several cloned rabbit organic electrolyte (OE) transporters expressed in cultured cells with their behavior in intact rabbit renal proximal tubules (RPT) to determine the contribution of each to basolateral uptake of the weak acid ochratoxin A (OTA) and the weak base cimetidine (CIM). The activity of organic anion transporters OAT1 and OAT3 proved to be distin...

A three-dimensional hydrodynamic model that includes a Lagrangian particle-tracking simulation was applied to the Danshuei River estuarine system in northern Taiwan. The model’s accuracy was validated with data from1999; the results from themodel agreedwellwith empirical observations ofwater surface elevation, tidal currents, and salinity. The validatedmodelwas then used to investigate the resi...

Particle filters is now established as one of the most popular method for visual tracking. Within this framework, it is generally assumed that the data are temporally independent given the sequence of object states. In this paper, we argue that in general the data are correlated, and that modeling such dependency should improve tracking robustness. To take data correlation into account, we prop...

The proteasome is an essential proteolytic machine in eukaryotic cells, where it removes damaged proteins and regulates many cellular activities by degrading ubiquitinated proteins. Its heterohexameric AAA+ ATPase Rpt subunits play a central role in proteasome activity by the engagement of substrate unfolding and translocation for degradation; however, its detailed mechanism remains poorly unde...

This intervention aimed to improve Badminton-specific functional performance of an elite under-19 player (18 years) via a single-weekly resistance and plyometric training (RPT) session for 8-weeks. The athlete’s ‘response-to’ and ‘withdrawal-from’ the RPT were assessed. The athlete (stature: 1.77 m, mass: 81.5 kg) completed the RPT intervention throughout a competitive season. Performance testi...

Oral NaCl produces a greater natriuresis and diuresis than the intravenous infusion of the same amount of NaCl. Gastrin is the major gastrointestinal hormone taken up by renal proximal tubule (RPT) cells. We hypothesized that renal gastrin and dopamine receptors interact to synergistically increase sodium excretion, an impaired interaction of which may be involved in the pathogenesis of hyperte...

INTRODUCTION No randomised, controlled trials have been conducted to date on the efficacy of psychological and pharmacological treatments of pain catastrophising (PC) in patients with fibromyalgia. Our aim in this study was to assess the effectiveness of cognitive-behaviour therapy (CBT) and the recommended pharmacological treatment (RPT) compared with treatment as usual (TAU) at the primary ca...