Despite much progress in mCRPC treatment in recent years, optimal treatment sequences are still unclear, particularly in the post-abiraterone or post-enzalutamide treatment space. For men with bone-predominant disease (ie, no visceral or bulky nodal metastases) and symptomatic progression, current offprotocol options include crossover therapy to another oral novel hormonal agent (enzalutamide t...

recurring after a short time, was successfully treated by radium. It is interesting to note in the present series (Cases 3 anid 4), the dlifference in response to radium of two growths which histologically are very similar. Generally it would seem if the situation of the growth is such that it (loes not reaclily permit of removal of a wedge of normal tissue together with the tumour, surgical in...

In medicine, assigning priorities for original ideas and for first implementation of a new type of treatment or technology-radium afterloading, for example-is often difficult. This situation is certainly true for radium therapy, with conflicting claims coming from France, Germany, and the United States about who first implemented it. Moreover, if possible, a distinction must be made between the...

background: vegetation (food stuff) is grown in soil that contains many radioactive elements such as 238u (uranium), 232th (thorium) and 40k (potassium), which may get deposited either due to radioactive fallout or/and by absorption from the soil and can pose serious health hazards. materials and methods: natural radioactivity, radiological hazards and annual effective dose assessment was carri...

As each year ushers in new and innovative survivalenhancing treatments for castration-resistant prostate cancer with bone metastases, patients and their physicians have a sense of empowerment associated with this growing therapeutic arsenal.1-5 Nonetheless, nearly 30,000 men still die from prostate cancer every year, and many have debilitating illness from osseous involvement. For this latter g...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Most patients with relapsed prostate cancer develop metastatic disease and eventually become castration-resistant. Skeletal metastasis is common in castrate resistant prostate cancer and is an independent poor prognostic factor (1). Furthermore, skeletal related events (SRE) such as spinal cord compression, pathologic...

In 1922 the Québec government appropriated $100,000 for the purchase of radium to found an Institut du Radium at the University of Montreal. Opened largely through the initiative and drive of Dr. Joseph-Ernest Gendreau, the institut was the first organization devoted to radium therapy and cancer treatment in Canada. This paper describes the background, origins and development of the Institut wi...

The radiation treatment of intra-oral cancer involves technics combining intra-oral radium applications directly to the primary seat of the disease and external radiation to the glandular regions of the neck. The problem of the primary lesion has been successfully met by electrosurgical methods, radium seed implantations directly into and about the site of the disease, and by heavily filtered r...

Radium-226, an alpha emitter with half-life 1600 years, is ubiquitous in natural environments. Present rocks and soils, it also absorbed by vegetation. The efficiency of 226Ra uptake plants from the soil important to assess for study heavy metals plants, monitoring radioactive pollution, biogeochemical cycle radium Critical Zone. Using a thoroughly validated measurement method effective concent...