Abstract OBJECTIVES Tumor Treating Fields (TTFields) is increasingly provided to patients with WHO grade 4 gliomas following radiotherapy. Particle beam radiotherapy (PBRT) represents a novel promising radiation approach improved therapeutic ratio. This study was aimed report an early result of TTFields in combination PBRT for treating based on prospective phase 2 trial from Shanghai Proton and...

Abstract BACKGROUND Resection of brain metastases (BM) close to the motor cortex and corticospinal tract (CST) bears a significant risk for treatment-related morbidity. Navigated transcranial mapping (nTMS) combined with diffusion-tensor-imaging (DTI) based fiber tracking (DTI-FTTMS) is valuable tool guide neurosurgeon along CST preserve function. This study aims proof practicability DTI-FTTMS ...

Abstract OBJECTIVE Immune checkpoint inhibitors (ICI) and stereotactic radiosurgery (SRS) are commonly utilized in the management of brain metastases. Treatment-related imaging changes (TRIC) a frequently observed clinical manifestation classified as radiographic radiation necrosis. However, these findings not well characterized may predict for response to SRS ICI. METHODS The diagnosis-specifi...

Abstract A phase I/IIa dose escalation trial was initiated to determine the safety and recommended II (RP2D) of 186RNL in patients with recurrent glioma. Liposomal rhenium-186 (186RNL) is a source high energy beta particles gamma photons attractive properties for brain CED.Patients biopsy proven glioma had computerized treatment planning placement up 4 intracranial catheter(s). Each patient rec...

Abstract BACKGROUND Interpretation of serial magnetic resonance imaging (MRI) for glioblastoma following radiation therapy (RT) is complicated by difficulty differentiating tumor from treatment-related changes, even using updated RANO criteria. The incorporation novel such as 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (18F-DOPA) PET/CT to post-treatment may improve prognostication and better ...

BACKGROUND Acute cervical adenitis can evolve into suppurative cervical lymphadenitis and may sometimes be associated with infection of the retropharyngeal and parapharyngeal spaces (i.e., retropharyngeal and poststyloid parapharyngeal abscesses). This study aimed to describe the clinical presentation of acute cervical lymphadenitis and infections of the retropharyngeal and parapharyngeal space...