Proteins in living organisms express various important functions by interacting with other proteins and molecules. Therefore, many efforts have been made to investigate and predict protein-protein interactions (PPIs). Analysis of strengths of PPIs is also important because such strengths are involved in functionality of proteins. In this paper, we propose several feature space mappings from pro...

Mature male rainbow trout have significantly higher relative ventricle masses (RVM, ventricle mass as a percentage of body mass) than do immature males or females. Hatchery-reared maturing male trout had a mean RVM of 0.139%, whereas females had an RVM of only 0.074 %. Moreover, as males matured and their testes grew from 0.07 to 3.92 % of body mass, RVM more than doubled. In female trout no su...

The relevance vector machine (RVM) is used to process the hyperspectral image in this paper to estimate the classifiers precisely in the high dimensional space with limited training samples. The detail of RVM is firstly discussed based on the sparse Bayesian theory. Then four multi-class strategies are analyzed, including One-vs-All (OAA), One-vs-One (OAO) and two direct multi-class strategies....

To define the relationship between the response – a random or dependent variable y and a predetermined or independent variable x, a straight line or concave respectively convex functions affected by random errors must be used. A locally weighted low-degree polynomial regression i.e. linear is fit to several subsets of data using linear least square fitting and a first-degree polynomial or the e...

Objective(s): Intracerebroventricular injection of orexin-A (hypocretin-1) antagonist has been shown to inhibit stress-induced analgesia. However the locations of central sites that may mediate these effects have not been totally demonstrated. This study was performed to investigate the role of rostral ventromedial medulla (RVM) orexin receptor 1 in stress-induced analgesia (SIA). Materials and...

Recent experiments with the bacteria Paenibacillus vortex reveal a remarkable strategy enabling it to cope with antibiotics by cooperating with a different bacterium-Escherichia coli. While P. vortex is a highly effective swarmer, it is sensitive to the antibiotic ampicillin. On the other hand, E. coli can degrade ampicillin but is non-motile when grown on high agar percentages. The two bacteri...

In patients with pulmonary arterial hypertension (PAH), right ventricular mass (RVM) correlates linearly with pulmonary artery pressure, and decreases with successful treatment. Accurate measurement of RVM currently requires cardiovascular magnetic resonance (CMR) imaging. We therefore tested the relationship between RVM and a simple, 12 lead ECG-derived value, the Butler-Leggett (BL) score. Th...

Previous studies have demonstrated that morphine, administered systemically or directly into the periaqueductal gray (PAG), produces a significantly greater degree of antinociception in males in comparison with females. Because the midbrain PAG and its descending projections to the rostral ventromedial medulla (RVM) constitute an essential neural circuit for opioid-based analgesia, the present ...

The Relevance Vector Machine (RVM) algorithm has been widely utilized in many applications, such as machine learning, image pattern recognition, and compressed sensing. However, the RVM algorithm is computationally expensive. We seek to accelerate the RVM algorithm computation for time sensitive applications by utilizing massively parallel accelerators such as GPUs. In this paper, the computati...

Relevance vector machines (RVM) have recently attracted much interest in the research community because they provide a number of advantages. They are based on a Bayesian formulation of a linear model with an appropriate prior that results in a sparse representation. As a consequence, they can generalize well and provide inferences at low computational cost. In this tutorial we first present the...