Background: Helicobacter pylori (H.pylori) infection causes multiple upper gastrointestinal diseases but optimal therapeutic regimen which can eradicate infection in all the cases has not yet been defined. This study was designed to evaluate the efficacy of triple levofloxacin-based versus clarithromycin-based therapy. Methods: In this open-label randomized clinical trial study 120 patients ...

CONTEXT The correct diagnosis and effective treatment of Helicobacter pylori gastric infection are essential in controlling this infection. OBJECTIVE To compare the diagnostic value of three tests based in endoscopic gastric biopsies histopathological evaluation with hematoxylin-eosin (H-E) staining, urease rapid test and microbiological culture for detecting Helicobacter pylori active infect...

Evaluation of Polymerase Chain Reaction (PCR) Using Tissue Sample from Rapid Urease Test Kit (CLO® Test) in the Detection of Helicobacter Pylori.: Comparison with PCR from Gastric Biopsy, Rapid Urease Test, and Histologic Result Sang Bae Kim, Woo Chul Chung, Eun Jung Kim, Hae Jung Sung, Yang Woon Lee, You Suk Oh, Chang Nyol Paik, Kang-Moon Lee Department of Internal Medicine, College of Medicin...

introduction: helicobacter pylori, as an etiologic cause of peptic ulcers and gastric cancer, should be tested and treated. the true state of infection can only be detected by isolation of gastric biopsies through the invasive method of gastroscopy. however, there are several non-invasive methods for detection of infection, the most common of which is serology. methods: here we have evaluated t...

BACKGROUND Despite a possible role of Helicobacter pylori in gastric carcinoma (GC), its pathogenesis is not clear. There is scanty data on apoptosis in GC in relation to H. pylori and CagA antibody. Therefore, we studied gastric epithelial apoptosis in GC and non-ulcer dyspepsia (NUD) with or without H. pylori infection, and the degree of apoptosis in relation to CagA antibody status. METHOD...

INTRODUCTION The sensitivity of invasive diagnostic methods for Helicobacter pylori (H. pylori) infection, particularly of urease rapid test, is decreased in cases of gastroduodenal ulcer and upper gastrointestinal bleeding. OBJECTIVES To assess the influence of blood in the stomach or recent bleeding endoscopic signs in the diagnostic sensitivity of urease rapid test among patients with blee...

BACKGROUND A rapid, reliable, and sufficiently accurate test for diagnosing Helicobacter pylori infection is required for screening dyspeptic patients before a referral for endoscopy. The purpose of this article is two-fold: first, to evaluate the accuracy of a one-step H. pylori saliva antigen (HPS) test; and second, to compare noninvasive and invasive H. pylori tests in Taiwanese population. ...

BACKGROUND H. pylori is a urease positive organism, and this activity in a gastric biopsy could be considered as a proof of the presence of H. pylori. For the reasons of high price and difficult accessibility to the commercial CLO-test in Iran, we designed an affordable equivalent test with high specificity, accuracy and availability. METHODS Biopsy samples from 80 symptomatic patients with g...

Infections with Klebsiella and Enterobacter have increased among hospitalized patients. To study such infections, relatively simple but precise methods are needed for clinical laboratories to identify the two genera accurately. Moreover, a rapid identification is essential for assisting with the therapy of the patients. For this purpose, a new 4-hr urease test was developed so that colonies cou...