We have examined the regulation of GH secretion from monolayer cultures of prepubertal male lamb anterior pituitary cells. Growth hormone-releasing factor (GRF 1-44) stimulated GH release in a dose-related manner : the maximal effective dose was 10IO M, which caused a 500 % increase in basal GH secretion, while the half-maximal effect was reached with a dose of 2.5 x 10-&dquo;M (ED 5Q ). Thyrot...

To determine whether long-term administration of growth hormone (GH)-releasing factor (GRF) and(or) thyrotropin-releasing hormone (TRH) alters ovarian follicular fluid (FFL) concentrations of insulin-like growth factor-I (IGF-I), progesterone, and estradiol (E2), and follicular growth, Friesian x Hereford heifers (n = 47; 346 +/- 3 kg) were divided into the following four groups: control (vehic...

BACKGROUND Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch continuously over prolonged periods of time. Kettlebell sport and weightlifting involve similar exercises, however, their traditional u...

A novel pituitary protein "7B2" was secreted by GH1 cells. The secretion of 7B2 was increased in the presence of human GRF in a dose-responsive manner. In contrast, a somatostatin analog, SMS 201-995, revealed the inhibitory effects on the basal- and GRF-induced secretion of 7B2 at the concentration of 10(-7) M. These findings suggest that 7B2 is a secretory protein of rat GH1 cells under certa...

Long-term administration of porcine growth hormone-releasing factor (pGRF(1-29)NH2) and(or) thyrotropin-releasing factor (TRF) was evaluated on serum concentrations of growth hormone (GH) thyroxine (T4) and prolactin (PRL). Twenty-four 12-wk-old female Yorkshire-Landrace pigs were injected at 1000 and 1600 for 12 wk with either saline, pGRF (15 micrograms/kg), TRF (6 micrograms/kg) or pGRF + TR...

Gibbs random eld (GRF) models and co-occurrence statistics are typically considered as separate but useful tools for texture discrimination. In this paper we show an explicit relationship between co-occurrences and a large class of GRF's. This result comes from a new framework based on a set-theoretic concept called the \aura set" and on measures of this set, \aura measures". This framework is ...

Accurate multidimensional ground reaction forces and moments (GRF/Ms) can be predicted from marker-based motion capture using Partial Least Squares (PLS) supervised learning. In this study, the correlations between known and predicted GRF/Ms are compared depending on whether the PLS model is trained using the discrete inputs of sex, height and mass. All three variables were found to be accounte...

In clinical gait analysis, ground reaction force (GRF) is the gait parameter which can validate the state of disorder of the patient's movement. The purpose of this study was to explore the possibilities of employing the GRF derived from kinematics of the center of gravity (COG) in the study of dynamics of human gait. Gait data was collected for healthy able-bodied men and women and patients af...

Biomechanical aspects of running injuries are often inferred from external loading measurements. However, previous research has suggested that relationships between external loading and potential injury-inducing internal loads can be complex and nonintuitive. Further, the loading response to training interventions can vary widely between subjects. In this study, we use a subject-specific comput...

Two experiments were conducted to determine the effects of immunoneutralization of growth hormone-releasing factor [GRF(1-29)-NH2] on concentrations of somatotropin (ST) and insulin-like growth factor I (IGF-I) in lactating beef cows. In Experiment 1, multiparous Hereford cows were immunized against 2 mg GRF(1-29)-(Gly)4-Cys-NH2 conjugated to human serum albumin (GRFi, n = 3) or 2 mg human seru...