OBJECTIVE Poststreptococcal reactive arthritis (ReA) is a (poly)arthritis presenting after a Streptococcus group A infection. Acute rheumatic fever (ARF), albeit caused by the same pathogen, has different risk characteristics and is considered to be a separate entity. Whereas ARF is known to cause carditis, the risk of carditis in adult poststreptococcal ReA is unknown. Consequently, the prevai...

The maintenance of the Mg(2+) balance of the body is essential for neuromuscular excitability, protein synthesis, nucleic acid stability, and numerous enzymatic systems. The Transient Receptor Potential Melastatin 6 (TRPM6) functions as the gatekeeper of transepithelial Mg(2+) transport. However, the molecular regulation of TRPM6 channel activity remains elusive. Here, we identified the repress...

A total of 110 clinical isolates of Clostridium difficile were analyzed by agarose gel electrophoresis by using both bacterial restriction endonuclease analysis (REA) and plasmid profiles. A total of 72 isolates were divided into 12 groups according to their REA patterns. Some 38 isolates exhibited unique patterns. Pattern A occurred in 20% of isolates. Isolates with patterns B, E, and G were c...

9 The objectives of this study were to estimate variance components, genetic 10 parameters, EBV, accuracies, and rankings for nine ultrasound and carcass traits in a 11 multibreed Angus-Brahman population using three genomic-polygenic models and one 12 polygenic model (PM). The genomic-polygenic models used the complete GeneSeek 13 GPF250k SNP set (GPM), top 5% SNP (GPMR1), and 5% SNP evenly sp...

OBJECTIVES Inflammatory arthritides/synovitides such as psoriatic (PsA), reactive (ReA) and rheumatoid (RA) arthritis share numerous immunopathological features, but develop different patterns of joint involvement. To investigate whether distinctive cell apoptosis may play a role in this context, we have assessed synovial cell apoptosis in situ in PsA and ReA, and compared it with RA and 'non-i...

Con urrent Obje t-Oriented Programs Sridhar Iyer. S. Ramesh. Dept. of Computer S ien e Dept of Computer S ien e IIT Guwahati IIT Bombay Guwahati, INDIA Mumbai, INDIA email : sri iitg.ernet.in ramesh se.iitb.ernet.in Abstra t The obje t-oriented paradigm has been found to be useful for the onstru tion of large and omplex onurrent systems. Rea hability analysis is an important and well-known tool...

The local T-cell response to bacterial antigens is involved in the pathogenesis of reactive arthritis (ReA). Here, we have identified a 19-kDa antigen of Yersinia enterocolitica O:9 recognized by Yersinia-specific synovial fluid CD4+ T cells in two patients with Yersinia-induced ReA. N-terminal amino acid sequencing of this protein revealed that it was identical to the 19-kDa urease beta subuni...

Applying object orientation to the task of modeling the value-added processes of a business enterprise is a task that should be examined both conceptually and practically. This paper does both, but its main theme is a conceptual reliance on a standardized object template -the REA (resource-event-agent) model -at various levels of abstraction as that template is used to model the economic activi...

The original REA accounting model (McCarthy, 1982) has been extended in previous years into a business modeling language. Apart from its conceptual model, academic effort has been put into the definition of a formal description language, based on standards such as UML or OWL. The specification of a generic data model from a software engineering point of view for domain independent use of REA fo...