Human endogenous retroviruses (HERVs) are discussed as causative agents of various diseases including cancers. Expression of endogenous retroviral sequences can be induced by ultraviolet (UV) light, which is also considered as a cofactor in the development of cutaneous melanoma. Therefore, we investigated whether ultraviolet C (UVC) induces HERV-K rec and np9 expression in normal human epiderma...

BACKGROUND To present empirical data on how the variation in regulating clinical research and patient care was perceived in Finland between 2009 and 2012. METHODS Notes of interviews with 22 research ethics committee (REC) chairpersons were analyzed to identify whether differences in the regulation of clinical research and patient care were addressed. REC chairpersons' opinions on three imagi...

Background: the Auditory Nerve Recovery Function (REC) may be extracted from the Electrically Evoked Compound Action Potential (ECAP). ECAP may be influenced by the stimulation received (or the deprivation of stimulation) and by the etiology of the hearing loss, consequently it might affect the REC. Aim: to verify whether there is a correlation between the REC and each of the following factors:...

UV-irradiated plasmid pNov1 containing a cloned fragment of chromosomal DNA could be repaired by excision, but plasmid p2265 without homology to the chromosome could not. Establishment of pNov1 was more UV resistant in Rec(-) than in Rec(+) cells.

Quantifying and verifying network reachability is important for security monitoring and auditing as well as many aspects of network management such as troubleshooting, maintenance, and design. Although attempts to model network reachability have been made, feasible solutions to computing network reachability have remained unknown. In this paper, we propose a suite of algorithms for quantifying ...

Complex research such as neuropsychiatric genetics presents unique challenges for ethics committees (REC), particularly in Africa where on mental & neurological disorders is still its infancy. To reflect these experiences of reviewing Neuropsychiatric Genetic studies we use two multicenter studies, the NeuroDev and NeuroGap-Psychosis studies. We explored content nation...

This study aimed to determine whether changes in contrast-enhanced computed tomography (CT) parameters could predict postsurgery overall and progression-free survival (PFS) in pancreatic cancer patients. Seventy-nine patients with a final pathological diagnosis of pancreatic adenocarcinoma were included in this study from June 2008 to August 2012. Dynamic contrast-enhanced (DCE) CT of tumors wa...

The benefit of Class-of-Service (CoS) is an important topic in the “Network Neutrality” debate. Some proponents of network neutrality suggest that over-provisioning is a viable alternative to CoS, and that there is no need for differentiated services in an IP backbone for users needing better-than-besteffort service. In this paper, we quantify the extra capacity requirement for an over-provisio...

We study the problem of answering k-hop reachability queries in a directed graph, i.e., whether there exists a directed path of length k, from a source query vertex to a target query vertex in the input graph. The problem of k-hop reachability is a general problem of the classic reachability (where k = ∞). Existing indexes for processing classic reachability queries, as well as for processing s...