OBJECTIVE To evaluate 2 active surveillance strategies for detection of enteric vancomycin-resistant enterococci (VRE) in an intensive care unit (ICU). DESIGN Thirty-month prospective observational study. SETTING ICU at a university-affiliated referral center. PATIENTS All patients with an ICU stay of 24 hours or more were eligible for the study. INTERVENTION Clinical active surveillanc...

BACKGROUND Drug resistant organisms pose an increasing threat to the successful treatment of common infections. Understanding colonization patterns of these bacteria is important for effective antibiotic treatment and infection control guidelines. METHODS A prospective observational study was performed to determine the prevalence of colonization with extended-spectrum β-lactamase-producing En...

background and objective: enterohemorrhagic escherichia coli (ehec) o157:h7 is an important enteric pathogen in human causing bloody or nonbloody diarrhea, which may be complicated by hemolytic uremic syndrome (hus). cattle are an important reservoir of ehec. this research aims at vaccination with a divalent chimer protein composed of espa 120 and intimin 282 and its preventive effect of ehec o...

Abstract Background The irrational use of carbapenems in the last years lead to emergence carbapenem-resistant Enterobacteriaceae (CRE). This study aimed at determining prevalence CRE intestinal carriage among admitted patients a tertiary care hospital Egypt, characterize carbapenemase-producing genes and identify possible risk factors colonization. One hundred rectal swabs were collected from ...

Background: Early-onset sepsis is a common cause of neonatal mortality and mainly occurs due to the colonized microorganisms in the maternal recto-vaginal area. The present study aimed to evaluate the effects of maternal risk factors on recto-vaginal colonization and transmission rate of micro-flora from mothers to infants. Methods: Upon admission, two samples were obtained from the distal thi...

The performance of StrepB Carrot Broth (SCB) versus group B Lim broth (LIM) for detection of group B streptococcus (GBS) colonization status in near-term pregnant women (35 to 37 weeks of gestation) was evaluated. Dually collected vaginal/rectal swabs from 279 women enrolled from a single large maternity clinic were analyzed. Fifty (18%) women were colonized by GBS according to both methods. SC...

Rapid identification of patients who are colonized with carbapenemase-producing organisms (CPO) is included in multiple national guidelines for containment of these organisms. In a multisite study, we evaluated the performance of the Cepheid Xpert Carba-R assay, a qualitative diagnostic test that was designed for the rapid detection and differentiation of the blaKPC, blaNDM, blaVIM, blaOXA-48, ...

OBJECTIVE To characterize the degree of colonization with multidrug-resistant organisms (MDROs) among patients admitted to a long-term acute care hospital. DESIGN Ecologic study. SETTING A 70-bed long-term acute care hospital (a hospital within a hospital) in the greater Chicago area. METHODS As part of an infection control initiative, specimens were collected from all consecutively admit...

Critical Care Medicine www.ccmjournal.org 565 C andida is the third most common agent responsible for healthcare-associated bloodstream infections and is the most common agent responsible for invasive fungal infections in children (1, 2). Candidemia is associated with a high mortality and morbidity among hospitalized patients as well as high healthcare costs (3). Prevalence of candidemia has dr...

Background Preterm birth complications are the leading cause of deaths among children <5 years of age. Studies have suggested that group B Streptococcus (GBS) maternal rectovaginal colonization during pregnancy may be a risk factor for preterm delivery. This article is the fifth of 11 in a series. We aimed to assess the association between GBS maternal colonization and preterm birth in order to...