Status epilepticus is a heterogeneous disorder with varied definitions and presentations. Taken together, all forms of status epilepticus carry significant morbidity and mortality, much of which is dictated by the underlying etiology. Generalized convulsive status epilepticus, which represents a common form, is a true neurologic emergency that requires emergent management. Treatment focuses on ...

Prolonged, refractory status epilepticus is a rare clinical syndrome that is associated with severe morbidity and mortality. Lacosamide is a newly approved medication for treatment of partial onset seizures in adults, which has a novel mechanism of action. Experimental data and recent reports suggest that lacosamide could be effective in status epilepticus. We report a child with prolonged, ref...

Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and an estimated mortality of 20 %. Clinically, tonic-clonic convulsive SE is divided into four subsequent stages: early, established, refractory, and super-refractory. Pharmacotherapy of status epilepticus, especially of it...

OBJECTIVE To look for pattern of non-convulsive status epilepticus in children with epilepsy at the Sultan Qaboos University Hospital, Sultanate of Oman. METHODS Twelve children (6 male and 6 female) with non-convulsive status epilepticus were seen at Sultan Qaboos University Hospital from December 1992 until December 1997. The diagnosis was suspected in children with previous history of seiz...

OVER the past 250 years, many accounts of status epilepticus have been published, but its true frequency is difficult to judge. Status epilepticus has been recognized as a clinical entity since 1824 when Calmeil first described patients who had repeated or prolonged uninterrupted epileptic seizures. It has been estimated that about 5% of all epileptic patients at some time in their lives experi...