conclusions the prevalence of ms showed an increasing rate of the disease in recent years. decreasing of the female to male ratio and patients’ low socio-economic level, need more studies. the increasing rate of patients with progressive relapsing feature and more disabled patients belong to this subtype show the poor prognosis. results a total of 142 patients were participated in this study. p...

conclusions the findings suggested that according to the ecological conditions of ahvaz, a family history of ms may increase the risk of developing ms. results in both cases and controls, no significant associations were found between arab ethnicity and incidence of ms, marital status and risk of ms in ahvaz, or more than 15-year residency in ahvaz, birth in khuzestan, and month of birth and th...

multiple sclerosis is a chronic inflammatory disease of central nervous system.women are more susceptible to this disease. one of the obvious clinical complaints in women with multiple sclerosis specially treated with beta interferones is menstrual cycle irregularity. the aim of this study was to determine the prevalence of menstrual irregularities and probable changes in blood levels of relate...

multiple sclerosis (ms) is a neuroinflammatory autoimmune disease which mediated by various molecular and cellular immune components however recent reports have shown that coagulation factors that traditionally separate from the immune system might also be involved in ms development and progression.studies on experimental autoimmune encephalomyelitis (eae) and human ms patients reports alterati...

multiple sclerosis (ms) is one of the autoimmune diseases with an unknown cause. the aim of this study was to explore the link between air quality and ms relapses in patients who suffer from ms.this time-series study was conducted on patients registered at the iranian multiple sclerosis society in 2011-2012. they were randomly selected from patients lived in tehran in the last five years, and h...

autoimmune diseases have been described as an interesting and poorly understood group of disorders. there are many challenges in the respective scientific societies concerning the nature, causes and the therapeutic approaches of these diseases. in accordance with the evidences the nature and etiology of these disorders is multifactorial and complex but the clearest definition could be expressed...

multiple sclerosis is an autoimmune disease caused by damage to the myelin of the nerve cells in the spinal cord and brain, ms was classified into 4 types including: relasping/remitting (rr) primary/progressive (pp), secondary/progressive (sp), progressive/relapsing (pr). pr ms is one of the severe forms of ms that lead to inflammation associated physical, mental and vision dysfunction. because...

noncoding ribonucleic acids micro-rna is involved in the regulation of gene expression have major roles in the post-transcriptional level. a micro-rna alone several causes down regulation of mrna transcript of the target. thus, small changes in the expression of a micro rna may lead to significant changes in gene expression are different. micro- rna as key regulators of immune cell lineage diff...

multiple sclerosis is an autoimmune disease of the central nervous system which its main characteristic is an inflammation and demyelination and subsequent, neural degeneration. many studies have shown that inflammation causing neuronal demyelination. ms is the most common cause of chronic neurological disability in during youth which the prognosis is that can be death. platelet activating fact...

guillain-barre syndrome (gbs) or acute idiopathic polyradiculoneuritis is an acquired immune-mediated inflammatory and mainly demyelinating disorder of the peripheral nervous system. cranial nerves are affected in over 50% of all cases, with the facial nerves being affected the most. it uncommonly presents as atypical forms such as brachial pharyngeal variant, miller fisher and other restricted...