We compared photopic and scotopic multifocal pupillographic stimuli in age-related macular degeneration (AMD). Both eyes of 18 normal and 14 AMD subjects were tested with four stimulus variants presented at photopic and 126 times lower luminances. The multifocal stimuli presented 24 test regions/eye to the central 60°. The stimulus variants had two different check sizes, and when presented eith...

STUDY OBJECTIVE The aim was to determine, employing non-invasive procedures, the prevalence of age related macular degeneration in persons 50 years of age and over. DESIGN A clinical investigation and a retrospective examination of ophthalmological records were employed in this study. SETTING The study was conducted over the period 1988 to 1990 in the Western Metropolitan Health Region of N...

As the medical community has accepted that age-related macular degeneration (AMD) is a disease influenced by genetics, so too has it uncovered patterns in patients’ genetic profiles that suggest some individuals are at increased risk for initiation or progression of the disease. However, genetics is not everything, and retina specialists need to remember that AMD is a complex disorder that is a...

Age-related macular degeneration is the leading cause of irreversible blindness in the United States and often coexists with chronic kidney disease. Both conditions share common genetic and environmental risk factors. A total of 1183 participants aged 54+ were examined in the population-based, prospective cohort Blue Mountains Eye Study (Australia) to determine if chronic kidney disease increas...