نتایج جستجو برای: related mucosal damage prophylaxis

تعداد نتایج: 1424708  

2001
Daniel D. Dressler Mark V. Williams Kimberly Rask

Background Stress-related gastric ulceration was first described in the early 1970s, and has since received extensive study. Appreciation of the physiologic changes that promote stress-related gastritis and general improvements in the care of critically ill patients have likely played a role in reducing the frequency of this complication. Nonetheless, the use of specific pharmacologic agents fo...

Journal: :Veterinary therapeutics : research in applied veterinary medicine 2006
Levent Dirikolu Wojciech Karpiesiuk Andreas F Lehner Charlie Hughes William E Woods John D Harkins Jeff Boyles Alfonza Atkinson David E Granstrom Thomas Tobin

Diclazuril is a triazine-based antiprotozoal agent which may have clinical application in the treatment of equine protozoal myeloencephalomyelitis (EPM). In this study, the use of the sodium salt diclazuril to increase the apparent bioavailability of diclazuril for the treatment and prophylaxis of EPM and various other Apicomplexan mediated diseases is described. In this study, diclazuril sodiu...

Journal: :The Journal of clinical investigation 1980
G D Luk T M Bayless S B Baylin

Diamine oxidase (histaminase) is an enzyme found in high concentrations in the intestinal mucosa of humans and other mammalian species. We investigated whether plasma and mucosal levels of diamine oxidase activity reflect both the maturational status of the mucosa during its development in the newborn rate and the degree of mucosal damage during its injury in the adult rat. Litter mates were re...

Journal: :The New England journal of medicine 2007
Marilyn J Manco-Johnson Thomas C Abshire Amy D Shapiro Brenda Riske Michele R Hacker Ray Kilcoyne J David Ingram Michael L Manco-Johnson Sharon Funk Linda Jacobson Leonard A Valentino W Keith Hoots George R Buchanan Donna DiMichele Michael Recht Deborah Brown Cindy Leissinger Shirley Bleak Alan Cohen Prasad Mathew Alison Matsunaga Desiree Medeiros Diane Nugent Gregory A Thomas Alexis A Thompson Kevin McRedmond J Michael Soucie Harlan Austin Bruce L Evatt

BACKGROUND Effective ways to prevent arthropathy in severe hemophilia are unknown. METHODS We randomly assigned young boys with severe hemophilia A to regular infusions of recombinant factor VIII (prophylaxis) or to an enhanced episodic infusion schedule of at least three doses totaling a minimum of 80 IU of factor VIII per kilogram of body weight at the time of a joint hemorrhage. The primar...

2015
Johannes Oldenburg

The key to a successful long-term outcome in patients with hemophilia is an efficient prophylaxis that prevents bleeding in joints for children and adults with hemophilia. Efficient prophylaxis requires taking into account the available resources (clotting factor concentrate, trough levels), the bleeding trigger (activity levels, chronic synovitis, already existing arthropathy), and most import...

Journal: :Gut 1991
W M Hui H Joana B W Chen C H Cho C T Luk S K Lam

Nicotine, while an important component of cigarettes, does not cause gross gastric mucosal damage, although its microscopic effect remains unknown. We have evaluated the histology and the microvascular permeability of (a) the effect of nicotine alone or in combination with ethanol on the gastric mucosa of rats and (b) the effect of feeding and sucralfate on the mucosa of rats treated with nicot...

منصف, علیرضا, هاشمی, سیدحمید,

Ischemic disease of the colon (Ischemic colitis) describe a more focal type of damage in the large intestine, increasingly recognized in the elderly. It is related to occlusion of the mesenteric artery, ligation during vatcular surgery, embolic episode, diabetes melitus, arthero sclerosis, polyarteritis nodosa, rheamatoid arthritis, systemic lupus erythematosus and amyloidosis.  Clinical...

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