alport syndrome is a progressive hereditary nephritis leading to renal failure. nearly all of the documents declare that alport syndrome is inherited as x-linked dominant trait and reports of autosomal inheritance form is very rare. this paper presents an iranian large alport family with autosomal recessive inheritance. in our patients alport disease was confirmed with electron microscopic stud...

background: patients with end‑stage renal disease (esrd) who receive dialysis confront the burdens of long‑term illness and numerous physical problems. materials and methods: this was a quasi-experimental study. the selected patients from gorgan dialysis centre were randomly assigned into an empowerment group ( n = 40) and a control group ( n = 40). instruments comprised scales of empowerment a...

introduction: this study aims to evaluate the dentomaxillofacial radiographic changes in end stage renal disease (esrd) patients who were on hemodialysis. methods: parathyroid hormone (pth), calcium, phosphorus and alkaline phosphatase (alp) measurements, as well as panoramic and periapical radiographs were obtained from seventy four patients with a history of end stage renal disease (esrd). re...

isolated hematuria and its association with proteinuria, and urinary cast and systemic lupus erythematosus (sle) disease activity, and decision for renal biopsy is a dilemma for physician in sle patients. the aim of this study was to investigate 1. whether isolated hematuria is associated with active sle, 2. to determine duration between hematuria and proteinuria and urinary cast, and 3. to det...

  Diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. It is the major cause of dialysis and transplantation. Failure in renal function causes wide disorders in the body. Diabetes results in wide range of alterations in the renal tissue. It is believed that early histological changes in diabetic nephropathy are detectabl...

Background: IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. Objective: To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. Methods: Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. B...

Renal anemia and chronic kidney disease-mineral bone disorder (CKD-MBD) are common in patients with disease (CKD). Blood metabolic biomarkers non-invasive indexes for evaluating renal osteodystrophy. Here the relationships between blood CKD investigated, effects of parathyroidectomy (PTX) on above indices analyzed.

anderson-fabry disease is a rare inherited x-linked lysosomal storage disease caused by deficiency of the enzyme alpha-galactosidase a. hereby we report a 39 year old male that presented with proteinuria and edema. histopathologic, immunofluorescence and ultrastractural examination of renal tissue were in favor  of  fabry disease in associate with iga nephropathy. fabry's disease associated wit...

background: primary infection with bk virus (bkv) is occurred during childhood and usually asymptomatic, but after initial infection, bkv may persist lifelong in the kidney and genitourinary tract. reactivation may occur in individuals with compromised immunity such as renal transplant recipients. due to the role of bkv in bk virus-associated nephropathy (bkvan) and potentially renal allograft ...