BACKGROUND AND OBJECTIVES Hyperuricemia is an independent risk factor for mortality, cardiovascular disease, and renal disease in general population. However, the relationship between hyperuricemia with clinical outcomes in CKD remains controversial. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The study investigated the association between uric acid with all-cause mortality, cardiovascular ...

PURPOSE OF REVIEW Timing of renal replacement therapy in critically ill patients with acute kidney injury is highly subjective, and may influence outcome. We discuss renal and nonrenal criteria for timing considering the recent literature. RECENT FINDINGS Two randomized and four nonrandomized controlled trials investigated the effects of timing on patient outcome. All but one randomized contr...

OBJECTIVES To identify prognostic factors in children receiving continuous renal replacement therapy. DESIGN Historical cohort study. SETTING Neonatal and paediatric intensive care unit of a Hong Kong hospital. PATIENTS Neonatal or paediatric patients who received continuous renal replacement therapy from January 1998 to December 2008. RESULTS In all, 37 patients who received 39 episode...

BACKGROUND Renal replacement therapy has been suggested as a therapeutic option in the setting of acute right ventricular failure in patients with severe precapillary pulmonary hypertension. However, there are few data supporting this strategy. OBJECTIVES To describe the clinical course and the prognosis of pulmonary hypertensive patients undergoing renal replacement therapy in the setting of...

Acute kidney injury is common in intensive care patients and continuous renal replacement therapy is the preferred treatment for this in most centres. Although these techniques have been adopted internationally, there remains significant variation with regard to their clinical application. This is particularly pertinent when one considers that the fundamental questions regarding any treatment, ...

OBJECTIVE To provide updated information (including on treatment) in relation to renal replacement therapy in critically ill patients. DATA SOURCES AND STUDY SELECTION Literature search of Medline and PubMed till June 2008. DATA EXTRACTION Original studies, literature review, and book chapters. DATA SYNTHESIS The prevalence of acute renal failure in critically ill patients remains high an...

There is an ongoing increase in the number of elderly or frail patients requiring renal replacement therapy. Assisted automated peritoneal dialysis (aAPD) is one treatment option for this patient group and is becoming increasingly recognized as a distinct dialysis modality. In this article, we review the current status of aAPD and its evolution across Europe, describing the differences in servi...

BACKGROUND Patients maintained on hemodialysis (HD) have an impaired health-related quality of life (HRQOL). One factor that has been suggested to contribute to this impairment is the prolonged recovery time after completing a conventional HD session. The present study was designed to carefully examine the time to recovery (TTR) in patients maintained on three times/week conventional HD and eva...