Introduction DSC-MRI has proven very useful for characterizing tissue perfusion indices such as CBF, CBV and MTT. However, since CBF and MTT only represent average capillary flow and transit time, a more exhaustive characterization of local capillary flow patterns could be achieved by estimating the entire underlying transit time distribution. Flow heterogeneity in particular, or analogously tr...

PURPOSE To determine the diagnostic value of a new ultrasmall superparamagnetic iron oxide Clariscan, (NC100150) for the evaluation of renal perfusion in an animal model using a 3D-FFE-EPI sequence. MATERIALS AND METHODS Four groups of four rabbits each were imaged after bolus injection of NC100150, using a 1.5 T MR system (Gyroscan ACS-NT). T2*w MR images in the coronal plane were acquired o...

The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastro...

BACKGROUND The hemodynamic evaluation of cerebral arteriovenous malformations (AVMs) using DSA has not been validated against true flow measurements. OBJECTIVE To validate AVM hemodynamics assessed by DSA using quantitative magnetic resonance angiography (QMRA). MATERIALS AND METHODS Patients seen at our institution between 2007 and 2016 with a supratentorial AVM and DSA and QMRA obtained b...

BACKGROUND/AIMS Achalasia is a primary motility disorder of esophagus. Many parameters represent esophageal function and morphologic changes, but their interrelationship is not yet established. We hypothesized that esophageal body would need to generate unusual pressure to empty the food bolus through the non-relaxing lower esophageal sphincter in patients with achalasia; therefore, higher is t...

This paper aims at incorporating tactical aspects of oil pipeline networks to the supply chain planning model. The strategic design of supply chains is covered in literature by well understood and recurring patterns such as multicommodity networks, dynamic parameters over time, capacity on facilities, transportation capacity or facilities with demand, production and inventory. We consider the f...

Modeling physiological processes using tracer kinetic methods requires knowledge of the time course of the tracer concentration in blood supplying the organ. For liver studies, however, inaccessibility of the portal vein makes direct measurement of the hepatic dual-input function impossible in humans. We want to develop a method to predict the portal venous time-activity curve from measurements...