Hepatic coma following acute hepatic necrosis carries a high mortality in spite of conventional therapy (Katz et al., 1962; McDonald and De la Harpe, 1963; Cook and Sherlock, 1965), but the concomitant development of renal failure makes the prognosis even worse (Hecker and Sherlock, 1956). Owing to the extraordinary capacity of the liver to regenerate, other forms of treatment have recently bee...

AIM To evaluate the efficacy of oral cyclosporin A in the prevention and treatment of immune graft rejection in heavily vascularised, repeated keratoplasties with high risk for failure. METHODS 21 consecutive patients with 28 repeated corneal transplants and four quadrant vascularised recipient bed were treated with oral cyclosporin A for an average period of 12 months (range 1-41 months) and...

KIRTI GUPTA, *SURJIT SINGH, *DHRUBAJYOTI SHARMA, #MINI P SINGH AND *MEENU SINGH From the Departments of Histopathology, *Pediatrics, and #Virology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Correspondence to: Dr Kirti Gupta, Associate Professor, Department of Histopathology, Postgraduate Institute of Medical Education and Research, (PGIMER), Chandigar...