Heat shock factor 1 (HSF1), in addition to its pivotal role as a regulator of the heat shock response, functions as a versatile gene repressor. We have investigated the structural domains involved in gene repression using mutational analysis of the hsf1 gene. Our studies indicate that HSF1 contains two adjacent sequences located within the N-terminal half of the protein that mediate the repress...

Empirical research on the social psychological antecedents of collective action has been conducted almost exclusively in democratic societies, where activism is relatively safe. The present examines predictors intentions contexts resistance met with significant repression by authorities. Combining recent advancements literature, our model unique predictive roles emotion (anger and fear), politi...

This special issue explores geographies of peace in violently contested cities – where the socio-political order is by actors who use violence and repression to either challenge or reinforce prevailing distribution power political, economic, social control. The articles within theorise explore where, when, how, why urban conflicts manifest themselves context cities. Together, they also uncover ...

In this paper we consider a triangular inter-dependence between hyperinflation, financial repression, and the crisis in FRY 1990s. When all three vertices of triangle are present, propagates is amplified along its edges. We focus, especially, on less studied link repression FRY. Setting administrative limits interest rates under conditions hyperinflation leads to deeply negative real rates. The...

This paper investigates the correlations between human rights situation and religious identity among minorities. It uses an integrated longitudinal dataset of World Values Survey waves from 1990 to 2014 three measures test how (a) constitutional guarantees freedom equality, (b) governmental practices, (c) societal discrimination prejudice against minority religions correlate with average streng...

PUF proteins regulate translation and mRNA stability throughout eukaryotes. Using a cell-free translation assay, we examined the mechanisms of translational repression of PUF proteins in the budding yeast Saccharomyces cerevisiae. We demonstrate that the poly(A)-binding protein Pab1p is required for PUF-mediated translational repression for two distantly related PUF proteins: S. cerevisiae Puf5...

MicroRNAs (miRNAs) regulate target mRNAs through a combination of translational repression and mRNA destabilization, with mRNA destabilization dominating at steady state in the few contexts examined globally. Here, we extend the global steady-state measurements to additional mammalian contexts and find that regardless of the miRNA, cell type, growth condition, or translational state, mRNA desta...

We examined relationships between repression, general maladjustment, body mass index (BMI), and waist-to-hip ratio (WHR). The participants were 1,081 healthy older men from the Normative Aging Study. Repression and General Maladjustment Scales of the Minnesota Multiphasic Personality Inventory were composite measures of personality. Repression was associated with lower BMI and WHR, and maladjus...

Despite constant monitoring, we lack a good explanation for the 2018–2019 protest crisis in Nicaragua. The escalation of protests, repression, duration, and death toll are surprising. Applying novel political economic cost framework, benchmark Nicaragua’s historical recent protests explain Ortega administration’s responses, thus providing rich case (with comparative data context) that makes sen...