Non-steroidal anti-inflammatory drugs (NSAIDs) are well recognised as causing peptic ulceration and ulcer complications. However, several critical issues, including the amount of both gastrointestinal and non-gastrointestinal disease affected by NSAIDs, their interaction with ancillary risk factors, and how to optimise management in subgroups, remain poorly understood. In this article, strategi...

Erythrocytes from a patient with classical pyrimidine nucleotidase (PyN) deficiency had less than 10% residual PyN activity with uridine 5'-monophosphate (UMP) or cytidine 5'-monophosphate (CMP) as substrate, but exhibited brisk nucleotidase activity with thymidine 5'-monophosphate (dTMP). This strongly suggests the existence of separate enzymes or isozymes of PyN in normal human erythrocytes--...

34 bronchial and 13 intercostal arteries were selectively embolized in 27 patients. the most frequent predisposing factor was either active or residual pulmonary tuberculosis. the procedure was performed with urografin as the contrast agent, cobra shaped or headhunter catheters, and gelfoam (no. 18) or ivalon (no. 9) particles. the most common anatomic pattern was a common bonchial artery trunk...

Alpha-cypermethrin (?-CP) a synthetic pyrethroid (type-II) insecticide, dissolved in dimethyl sulfoxide (DMSO-1ml) given consecutive daily orally for 60 days at 1/10LD50 (14.5mg/kg). The animals were sacrificed on day 61st. Biochemicals, cytochromeP450, b5 contents in liver along with antioxidant status, tissue residual concentration, and brain GABA level were studied. It increased the serum am...

Determination of drug residues in food is of great importance due to their toxicity. Long-term exposure with low level of drug residues could be important, especially in children. Based on document study, oxytetracycline (OTC) is a prophylaxis and treatment agent for great number of diseases and possesses a broad spectrum activity against many pathogenic organisms and can be toxic or cause alle...

the ponseti method is a safe and effective treatment for congenital clubfoot, and radically decreases the need for extensive corrective surgery. but a group of patients will still present with under corrected residual equinovarus deformities despite the proper use of the ponseti method. about 25% of operated clubfeet will develop recurrence or show a marked residual deformity (recurrent clubfoo...

Soil ammonium toxicity can decrease plant growth, and many crop species have low resistance to ammonium, including canola, an economically important crop. Different genotypes may differ in their toxicity, therefore determining if there are that exhibit variation ability tolerate soil is a research priority. Here, we evaluate how impacts canola root shoot growth characterise differences among re...

34 bronchial and 13 intercostal arteries were selectively embolized in 27 patients. The most frequent predisposing factor was either active or residual pulmonary tuberculosis. The procedure was performed with Urografin as the contrast agent, cobra shaped or headhunter catheters, and gelfoam (no. 18) or Ivalon (no. 9) particles. The most common anatomic pattern was a common bonchial artery ...

The ability of hyperantigenic preparations of synthetically produced Escherichia coli heat-stable toxin (ST) to provide an immunogenically more potent vaccine when cross-linked by the glutaraldehyde reaction to the heat-labile toxin B subunit was assessed. Three synthetic ST preparations were evaluated: ST(S) had the same antigenicity and toxicity (secretory potency in the suckling mouse assay)...

. Abstract: The liquid eftluent from an oil maritime terminal, with produced water as the main component, had its toxicity evaluated through toxicity tests with the diatom Skeletonema costatum. Two previously treated eftluent samples (eftluents A and B), were provided by PETROBRAS for the experiments. Both samples presented high salinity (67%0for eftluent A and 62%0for eftluent B) and low pH va...