background: in this work investigation of the normoxic pagat polymer gel dosimeter such as sensitivity, the r2-dose response with post time and the percentage depth dose (pdd) of pagat polymer gel dosimeter have been undertaken. materials and methods: using mri, the formulation to give the maximum change in the transverse relaxation rate r2 was determined to be 4.5% n,n'-methylenbis- acryl...

a young known case of multiple sclerosis was evaluated with chief complaint of gradually progressed left lower limb weakness over 3 weeks. pathologic examination of a mass in brain magnetic resonance imaging confirmed the diagnosis of glioblastoma multiforme (gbm). given the importance of the definite diagnosis of malignant glioma and its effect on patient’s management, gbm should be considered...

background: magnetic resonance imaging (mri) has improved the diagnosis and management of patients with multiple sclerosis (ms). montreal cognitive assessment (moca) is a brief, sensitive test that has been recommended by national institute of neurological diseases and stroke and canadian stroke network (ninds-csn) as a reliable tool to detect mild cognitive impairments. this study aimed to eva...

In patients who present with a clinically isolated syndrome (CIS), whose features are suggestive of multiple sclerosis (MS), fulfilling McDonald 2010 magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) and dissemination in time (DIT) enables a diagnosis of MS. While ⩾1 periventricular lesion is included in the 2010 DIS criteria, earlier McDonald criteria required ⩾3 periv...

Background: The integration of different imaging technologies such as computed tomography (CT) and magnetic resonance (MRI) assists clinicians in diagnosing several neurological diseases at an initial stage, thereby inhibiting their development into serious medical conditions. With respect to the severity increasing popularity tools, current study has evaluated findings CT MRI examining disorde...

Medical Resonance Imaging (MRI) is non-radioactive-based medical imaging that provides a super-resolution of tissues. However, because its complex nature using existing Deep Learning-based noise removal (i.e., Denoising) techniques, the reconstruction quality poor and time-consuming. An extensive study shows very limited work has been done on Brain Multiple Sclerosis (MS) Lesions MRI. Designing...

Bimodal imaging combines two imaging modalities in order to benefit from their advantages and compensate the limitations of each modality. This technique could accurately detect diseases for diagnostic purposes. Nanoparticles simultaneously offer diagnostic data via various imaging modalities owing to their unique properties. Moreover, bimodal nanoprobes could be incorporated into theranostic s...

Tumefactive demyelinating brain disease can pose a diagnostic challenge in patients without a pre-existing diagnosis of multiple sclerosis by mimicking intra-cranial neoplasms, infarction, as well as infections. Choosing when to biopsy a tumefactive lesion to exclude alternative pathology can be difficult. Here we report a case of a 44 year old female patient without a previous history of multi...

background: the aim of this study was to estimate the conversion rate from radiologically isolated syndrome (ris) to definite multiple sclerosis (ms). methods: during a mean (standard deviation [sd]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with ris and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite ms. ...

MRI is used routinely in clinical practice and pharmaceutical trials to measure disease activity and assess the effects of treatment in multiple sclerosis. Conventional MRI techniques sensitively detect inflammation, demyelination, and tissue injury. Less conventional imaging modalities, such as magnetic resonance spectroscopy and magnetization transfer imaging, and advanced image processing to...