Current modalities of ventilatory assistance in the management of respiratory distress syndrome (RDS) in preterm infants range from continuous positive airway pressure (CPAP) to various modes of mechanical ventilation. The use of CPAP has been associated with a lower incidence of chronic lung disease when used as the initial respiratory support. In contrast, mechanical ventilation has the poten...

OBJECTIVE To determine the effect of birth order on respiratory distress syndrome (RDS) in the outcome of twins in a large premature population managed in a modern neonatal intensive care unit. METHODS An historical cohort study design was used to analyse the neonatal outcomes of 301 premature liveborn twin sibling pairs of between 23 and 31 weeks gestation from the Australia and New Zealand ...

background: using of natural and synthetic surfactant is a rescue treatment for respiratory distress syndrome. in iran, survanta and curosurf are the most frequent used natural surfactant preparations. we compared the clinical response and safety of two surfactants poractant alpha (curosurf) and beractant (survanta) for treatment of respiratory distress syndrome (rds) in preterm infants. method...

Despite recent advances in the perinatal management of neonatal respiratory distress syndrome (RDS), controversies still exist. We report updated recommendations of a European Panel of expert neonatologists who developed consensus guidelines after critical examination of the most up-to-date evidence in 2007 and 2010. This second update of the guidelines is based upon published evidence up to th...

Background: Early nasal continuous positive airway pressure (NCPAP) has emerged as a primary modality of respiratory support for preterm infants withrespiratory distress syndrome (RDS). However, 30%-40% of these newborns need subsequent mechanical ventilation. Nasal intermittent positive pressure ventilation (NIPPV) is a promising alternative to NCPAP, especially in po...

Nitric oxide mediates multiple physiological functions, including neurotransmission, immune regulation, angiogenesis, antiplatelet activity, and surfactant maturation or secretion. Mice deficient in the nitric oxide synthase 3 (NOS3) gene displayed defective lung vascular development and fatal respiratory distress. Polymorphisms in NOS3 have been reported to be associated with respiratory distr...

Continuous positive airway pressure (CPAP) has become a useful modality in management of respiratory distress, especially in preterm babies. Main indications for use of CPAP are respiratory distress syndrome (RDS) and apnea of prematurity. It decreases the need of invasive and costly mechanical ventilation. This review details the physiological effects of CPAP, its methods of delivery, and its ...

Hydrocortisone (100 mg in a single injection) was given to 120 pregnant women with threatened premature delivery. None was given to a control group of 40 mothers. Orciprenaline was also given to all the mothers to inhibit uterine activity. The administration of hydrocortisone did not accelerate delivery and in the treated group 55 babies were eventually born at term; none died or had perinatal ...

OBJECTIVE To estimate direct medical costs (DMC) associated with treatment of Respiratory Distress Syndrome (RDS) in newborns (NB) in two specialized public hospitals in Mexico. MATERIALS AND METHODS The perspective used was health care payer. We estimated DMC associated with RDS management. The pattern of resource use was established by reviewing clinical records. Microcosting and bootstrap ...