Acute respiratory distress syndrome (ARDS) is a clinical syndrome of severe dyspnea of rapid onset, hypoxemia, and diffuse pulmonary infiltrates leading to respiratory failure. ARDS is caused by diffuse lung injury from many underlying medical and surgical disorders. The lung injury may be direct, as occurs in toxic inhalation, or indirect, as occurs in sepsis ( Table 268-1 ) . The clinical fea...

VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...

VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...

Submit Manuscript | http://medcraveonline.com First described by Ashbaugh in 1967, ARDS was observed in combat patients who developed respiratory distress, diffuse lung infiltrates, and respiratory failure despite oxygen therapy after occurrence of nonthoracic injuries, severe pancreatitis, massive transfusions, sepsis and various other insults [2]. As compared to decades ago, today, clinicians...

ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) is a clinical condition characterized by impaired gas exchange as a result of the accumulation of edema in the alveolar space. The clinical management of ARDS patients includes mechanical ventilation with high oxygen concentrations. Mechanical ventilation alleviates the work of breathing and hypoxemia while allowing time for the lungs to recover from t...

VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...

C onsidering the complex series of cardiorespira-tory changes that occurs at birth, it is not surprising that the transition to extrauterine life does not always proceed smoothly. Neonatal respiratory disorders account for the majority of admissions to intensive care units and result in significant morbidity and mortality. Once the infant shows signs of respiratory distress, prompt diagnosis is...