A hydrothermal method for preparation of nano-size zirconia has been studied to optimize the effective parameters (precursor concentration, temperature and time) using response surface methodology (RSM). The synthesized zirconia samples were characterized through X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscopy (TEM) analyses to identify mean nano...

In the present study Response surface methodology (RSM) was used to investigate the combined effect of relevant process variables to maximize the production of xylanase in submerge fermentation by Penicillium citrinum MTCC 2553. The process variables include pH (6.5, 7.0, and 7.5); temperature (25, 30, and 35°C); agitation speed (190, 200, and 210 rpm); and, substrate (xylan) concentration (0.7...

Liposomes are the most important lipid-based nanocarriers, which are used for encapsulation of both hydrophilic and hydrophobic active compounds. The aim of this study was to investigate the effect of Gammaoryzanol (GO) addition to lipid bilayers on characteristics of liposomes prepared by a modified ethanol injection method. The GO bearing nanoliposomes were prepared with different molar ratio...

The purpose of this study is to optimize adsorption conditions of powdered alum sludge (PAS) as low-cost adsorbent for the removal of three P-species (ortho-P, poly-P and organic-P) from wastewater using the response surface methodology (RSM). Initially, RSM in the basis of a 3-variable Box-Behnken design was used to determine the effect of pH (from 4 to 7), PAS mass (from 0.1 to 0.5 g) and PAS...

In recent years, the fascinating range of Response surface methodology (RSM) applications has captured interest many researchers and engineers worldwide. RSM is entirely based on well-known regression principles variance analysis that enable user to improve, develop optimize process or product under study. An overview theoretical RSM, experimental strategy its tools components, along with pros ...

Homogenate extraction method was applied to fast extraction of polysaccharides from loquat leaves. Factors which affected extraction yield were investigated and optimized by response surface methodology (RSM). Results showed that optimum technological conditions were as follows: ratio of liquid to material, 25 ml: 1g; extraction time, 100 s; and pH of extracting solvent, 11. Under optimum condi...

With the aim of improving nutritional profile and antioxidant capacity of gluten-free cookies, blueberry pomace, byproduct of juice production, was processed into a new food ingredient by drying and grinding and used for a gluten-free cookie formulation. Since the quality of a baked product is highly influenced by the baking conditions, the objective of this work was to optimize the baking time...

This study aims to extract Glycyrrhizic Acid (GA) from Glycyrrhiza glabra L. (licorice) using a novel, high efficiency, and low-cost extraction method. Water was chosen as the proper solvent for the extraction process to eliminate the requirement of harmful and toxic solvents, prepare an environmentally friendly process, and reduce the costs. The effect of differe...