Escape mutant (EM) virus that evades CD8+ T cell recognition is frequently observed following infection with HIV-1 or SIV. This EM virus is often less replicatively "fit" compared to wild-type (WT) virus, as demonstrated by reversion to WT upon transmission of HIV to a naïve host and the association of EM virus with lower viral load in vivo in HIV-1 infection. The rate and timing of reversion i...

We carry out a Monte-Carlo simulation of a standard portfolio management strategy involving derivatives, to estimate the sensitivity of its downside risk to a change of mean-reversion of the underlyings. We find that the higher the intensity of mean-reversion, the lower the probability of reaching a pre-determined loss level. This phenomenon appears of large statistical significance for large e...

If f = EW:-, a,,t” is a formal Laurent series with certain restrictions on the a,, then f = f-fof+ , where fcontains only negative powers of t, f+ contains only positive powers of t, and f. is independent of t. Applications include Lagrange’s formula for series reversion, the problem of counting lattice paths below a diagonal, and a theorem of Furstenberg that the diagonal of a rational power s...

We study a financial market where asymmetric information, mispricing and jumps exist, and link the random optimal portfolios of informed and uninformed investors to the deterministic optimal portfolio of the symmetric market, where no mispricing exists. In particular, we show that under quadratic approximation, the expectation of the random optimal portfolio in the asymmetric market is equal to...

The precipitation, coarsening and reversion of carbides can determine the quality of steels. This paper is a review of efforts towards better, practical theory for all of these solid–state reactions.

In this paperwe testwhethermean reversion in stockmarket prices presents a different behavior in bull and bear markets. We date the US bull and bear periods using Bry and Boschan (1971) algorithm. We examine the order of integration in the S&P 500 stock market index covering a daily period from August 1929 to December 2006 in bull and bear phases. Our results indicate the existence of different...

This paper investigates changes in the long-horizon behaviour of stock prices. Using a time-varyingparameter framework, we find that any pre-World War II tendency for mean reversion disappearsduring the post-War period. Furthermore, when we account for changes in the market risk premiumdue to dramatic shifts in pre-War return volatility, the full sample evidence for mean reversion i...

BACKGROUND We previously used a three-dimensional (3D) reconstituted basement membrane (rBM) assay to demonstrate that tumorigenic HMT-3522 T4-2 human breast cells can be induced to form morphologically normal structures ("reversion") by treatment with inhibitors of beta1 integrin, the epidermal growth factor receptor (EGFR), or mitogen-activated protein kinase (MAPK). We have now used this ass...

In this paper, we study the Heston stochastic volatility model in the regime where the maturity is small but large compared to the mean-reversion time of the stochastic volatility factor. We derive a large deviation principal and compute the rate function by a precise study of the moment generating function and its asymptotic. We then obtain asymptotic prices for Out-of-The-Money call and put o...