several cell lines (18) of poorly differentiated rat ascites hepatomas which grown intraperitoneally were analyzed with respect to their mrna levels of gst-p and albumin. the expression of albumin was dramatically decreased and became undetectable in all of the examined hepatomas compared with normal rat liver. the gst-p mrna level in the hepatomas was correlated with their ability for formatio...

foot-and-mouth disease (fmd) is a severely contagious viral disease that mainly affects cloven-hoofedlivestock and wildlife. this study quantifies the cytokines mrna expression of vaccinated guinea pigs withfmd type o inactivated vaccine. blood samples were collected from eight guinea pigs at 7 and 28 days after thefirst vaccination. extracted mrnas were reverse-transcribed into cdna and analyz...

the ataxia telangiectasia mutated gene (atm), candidate for breast cancer susceptibility gene, encode a 350-kda protein belongs to the core components of dna-damage response machinery. female at carriers have at least 5-fold increase risk for breast cancer. reduction in atm expression is shown in multiple studies in breast tissues. we aimed to perform a research to measure the atm mrna expressi...

objective(s): haemostasis prevents blood loss following vascular injury. it depends on the unique concert of events involving platelets and specific blood proteins, known as coagulation factors. the clotting system requires precise regulation and coordinated reactions to maintain the integrity of the vasculature. clotting insufficiency mostly occurs due to genetically inherited coagulation fact...

objective: chronic myeloid leukemia (cml) is a malignant clonal disorder of hematopoietic stem cells which results in increase of myeloid cells, erythroid cells and platelets in the peripheral blood and hyperplasia in bone marrow. investigations have shown different types of bcr- abl variants in these patients. in iran only 3 types of these variants have been identified because most of the clin...