نتایج جستجو برای: rheumatoid factor rf
تعداد نتایج: 922080 فیلتر نتایج به سال:
Background: The anti-cyclic citrullinated peptide (CCP) test has a high sensitivity and specificity for rheumatoid arthritis, although CCP is not the physiological target of the autoantibodies. Citrullinated fibrin is abundant in inflamed synovium Objective: To assess the diagnostic and prognostic value of antibodies against citrullinated fibrinogen (ACF), a soluble precursor of fibrin, in comp...
The major rheumatoid factor cross reactive idiotype (RCRI), defined by prototypic monoclonal rheumatoid factors (RFs), is expressed as a dominant idiotype by pokeweed mitogen induced plasma cells obtained from seropositive (RF+) patients with rheumatoid arthritis (RA). Some patients who meet clinical diagnostic criteria for RA set by the American Rheumatism Association fail to express RFs at an...
OBJECTIVE The main genetic risk factor for rheumatoid arthritis (RA) is the shared epitope (SE) of HLA-DR, while smoking is an important environmental risk factor. We studied a potential gene-environment interaction between SE genes and smoking in the etiology of the 2 major subgroups of RA: rheumatoid factor (RF)-seropositive and RF-seronegative disease. METHODS A population-based case-contr...
This report deals with the question of whether or not the established association of HLA-DR4 with rheumatoid arthritis (RA) can also be detected in cases of RA as diagnosed in a population survey. For this purpose 6584 persons older than 19 years living in a single community in The Netherlands were investigated for the presence of rheumatoid arthritis and related abnormalities. After five years...
OBJECTIVE To determine whether rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP) antibodies, or carriage of shared epitope (SE) and PTPN22 genetic susceptibility variants predict response to therapy in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor (TNF) agents. METHODS UK-wide multicentre collaborations were established to recruit a large cohor...
I n this issue of the Annals, Freemer et al report an association between smoking and dsDNA autoantibody production in systemic lupus erythematosus (SLE). The authors note that exposure to tobacco smoke has previously been associated with several autoimmune diseases, including rheumatoid arthritis (RA) and SLE. In RA, cigarette smoking has been associated with rheumatoid factor (RF) positive bu...
OBJECTIVE To examine the association between HLA-DRB1 alleles and the production of anti-cyclic citrullinated peptide (anti-CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). METHODS We studied 1,723 Caucasian RA patients enrolled in the North American Rheumatoid Arthritis Consortium (NARAC) family cohort and the Study of New Onset Rheumatoid Arthritis ...
Arthritis is one of the common diseases. in this present study twenty patients with symptoms of arthritis were included is as control another twenty patients without arthritis are included. The serum samples of these patients were collected and left for RF(or) RA which detects the immunoglobulin of the class IgM, IgA and IgE and careful prognostic marker of RA ie IgM is detected. Different reag...
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