نتایج جستجو برای: rif
تعداد نتایج: 2771 فیلتر نتایج به سال:
Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif(r)) in 100 isolates (82 Rif(r)) from three states of Brazil were studied. Twenty-one different kinds of mutations were identified in the Rif(r) isolates, and six new alleles are described.
BACKGROUND Since 2004, treatment of Mycobacterium ulcerans disease, or Buruli ulcer, has shifted from surgery to daily treatment with streptomycin (STR) + rifampin (RIF) for 8 weeks. For shortening treatment duration, we tested the potential of daily rifapentine (RPT), a long-acting rifamycin derivative, as a substitute for RIF. METHODOLOGY/PRINCIPAL FINDINGS BALB/c mice were infected with M....
مساله کمترن توان های دوم از اهمیت فراوانی در آنالیز عددی است. در این پایان نامه به بررسی روش های تکراری cgnr cgne lsqr ba-gmres و ab-gmres برای حل مساله کمترین توان های دوم می پردزیم. همچنین پیش شرط سازی این روش های تکراری را با پیش شزط rif و مقیاس بندی قطری ارائه می دهیم و نشان می دهیم روش های ba-gmres ab-gmres و cgnr cgne پیش شرط شده رفتار همگرایی مشابهی برای مسائل فرومعین (فرامعین) دارند. ...
Sixty rifampin (RIF)-resistant and 75 RIF-susceptible Mycobacterium tuberculosis isolates from Shandong Province, China, were analyzed for rpoB gene mutations and genotyped. Mycobacterial interspersed repetitive unit (MIRU) genotype 223325173533 was overrepresented among RIF-resistant isolates. MIRU combined with IS6110 restriction fragment length polymorphism analysis as the second-line genoty...
OBJECTIVES The efficacy of rifampicin-loaded polymeric microspheres (RPLGA) delivered to guinea pigs infected with Mycobacterium tuberculosis (H37Rv) was compared with a daily dose of nebulized rifampicin suspension. METHODS Aerosol-infected animals were subjected to multiple dose or single dose treatment with RPLGA, PLGA microspheres or micronized rifampicin suspension aerosols. For comparis...
BACKGROUND/AIMS The use of genetic probes for the diagnosis of pulmonary tuberculosis (TB) has been well described. However, the role of these assays in the diagnosis of intestinal tuberculosis is unclear. We therefore assessed the diagnostic utility of the Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) assay, and estimated the prevalence of multidrug-resistant (MDR) TB in the Indian pop...
18 Objectives: To monitor the stability of rifampicin (RIF) in Löwenstein-Jensen medium (L-J 19 medium) and 7H9 broth, which are the commonly used media for drug susceptibility testing (DST) 20 for Mycobacterium tuberculosis. Methods: Rifampicin degradation in stock solution, 7H9 broth, 21 L-J medium, and during the inspissation process for L-J medium preparation was serially 22 monitored by hi...
BACKGROUND Mycobacterium tuberculosis remains one of the most significant causes of death from an infectious agent. Rapid and accurate diagnosis of pulmonary and extra-pulmonary tuberculosis (TB) is still a great challenge. The GeneXpert MTB/RIF assay is a novel integrated diagnostic system for the diagnosis of tuberculosis and rapid detection of Rifampin (RIF) resistance in clinical specimens....
Because rifampin (RIF) induces hepatic enzymes and inhibits uptake transporters, dosing a drug that is a dual substrate of enzymes and uptake transporters on the final day of an inducing regimen should exhibit less inductive effect than dosing on the following day in the absence of RIF, since RIF decreases drug uptake into liver. In vitro and in vivo rat studies were conducted using digoxin as ...
BACKGROUND Global control of tuberculosis is hampered by slow, insensitive diagnostic methods, particularly for the detection of drug-resistant forms and in patients with human immunodeficiency virus infection. Early detection is essential to reduce the death rate and interrupt transmission, but the complexity and infrastructure needs of sensitive methods limit their accessibility and effect. ...
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