PURPOSE To determine whether nucleolar diameter and microvascular factors are independent predictors of mortality in malignant uveal melanoma of the choroid and ciliary body. METHOD A population-based retrospective cohort study was conducted of melanoma-specific and all-cause mortality in 167 consecutive patients who had an eye enucleated because of choroidal and ciliary body melanoma from 19...

are reported in the literature and only one of them is a ciliary body neurilemmoma. This is not correct, because according to Shields et al.2 (not cited) the reported cases of neurilemmoma are eight at least (associated and unassociated with neurofibromatosis), and two ofthem affected the ciliary body. Secondly, I would point out that in the case reported a fine needle aspiration biopsy could b...

Purpose: To describe the case of a 21-year-old patient with uveal effusion with no microphthalmia and any systemic disease that was treated with scleral window surgery and topical administration of mitomycin C (MMC) and zonulysis which was misdiagnose as a ring melanoma of cilliary body appeared shortly after the operation Case report: A uveal effusion was detected in the eye. Partial-thickness...

A 67-year-old man presented with a diffuse choroidal and ciliary body infiltrate, suggesting clinically and ultrasonographically a diffuse uveal melanoma. After enucleation both morphological and immunohistochemical data were highly suggestive of a diffuse, low-grade B cell lymphoma or lymphoplasmacytic immunocytoma. The difficulties of clinical and histopathological differential diagnosis of u...

This is the first report of an amelanotic melanoma arising in the unpigmented choroid of a tyrosinase-positive oculocutaneous albino (TPOCA). Melanosomes within the tumour showed a maturation arrest in the unpigmented type II (premelanosome) phase. Other neural crest derived melanocytes in iris and choroid showed similar limited melanogenesis. The neuroectodermally derived melanocytes of the ir...

Both the basal body and the microtubule-based axoneme it nucleates have evolutionarily conserved subdomains crucial for cilium biogenesis, function and maintenance. Here, we focus on two conspicuous but underappreciated regions of these structures that make membrane connections. One is the basal body distal end, which includes transition fibres of largely undefined composition that link to the ...