INTRODUCTION Balanced chromosomal translocations are a relatively common (2-7%) finding among infertile couples. We report clinical features of males with translocations at our institution. MATERIALS AND METHODS Data was collected on men presenting for infertility evaluation between July 2006 March 2010, including presentation, medical history, and infertility treatments. Criteria for genetic...

Mosaicism for trisomy of chromosome 14 (T14) is a very rare chromosomal disease in liveborn patients. Since the 1970s, when first patients with mosaicism T14 were reported, number studies on clinical manifestations this abnormality have been published. No information epidemiological parameters was known except rarity and its predominance among female carriers. This systematic review published c...

Robertsonian translocations (RTs) are very common balanced structural chromosome rearrangements in humans. Due to alterations the segregation pattern and formation of unbalanced gametes embryos, carriers RTs have a significant risk reproductive failure. For over 30 years, fluorescent situ hybridization (FISH) has been used for preimplantation genetic testing chromosomal rearrangement (PGT-SR) R...