نتایج جستجو برای: rora
تعداد نتایج: 204 فیلتر نتایج به سال:
To interrogate the alternative fates of pancreas and liver in the earliest stages of human organogenesis, we developed laser capture, RNA amplification, and computational analysis of deep sequencing. Pancreas-enriched gene expression was less conserved between human and mouse than for liver. The dorsal pancreatic bud was enriched for components of Notch, Wnt, BMP, and FGF signaling, almost all ...
The expression of retinoid-acid-related orphan receptor α (RORα) was evaluated at the mRNA level using real-time polymerase chain reaction (qRT-PCR), and its expression localization was determined by in situ hybridization of adult Inner Mongolian cashmere goats at different times of the year. In situ hybridization demonstrated that RORαwas expressed in secondary hair follicles of the hair shaft...
We sought exonic transcriptional regulatory elements by shotgun cloning human cDNA fragments into luciferase reporter vectors and measuring the resulting expression levels in liver cells. We uncovered seven regulatory elements within coding regions and three within 3' untranslated regions (UTRs). Two of the putative regulatory elements were enhancers and eight were silencers. The regulatory ele...
AIM The aim of this study was to investigate the expression of melatonin receptor MTNR3 and nuclear receptors in murine lymphocytes and their dependence on lighting conditions and circadian time. MATERIALS AND METHODS The mRNA levels of melatonin receptors were investigated in cells isolated from thymus, spleen, lymph nodes and bone marrow during the day or during the night. RESULTS The exp...
Shift work which causes circadian disruption is an established cancer risk factor. A large body of experimental and epidemiological data proves that exposure to light at night promotes carcinogenesis in various tissues and accelerates aging [1-3]. Artificial or natural light through master clock located in suprachiasmatic nuclei of hypothalamus suppresses night peak of melatonin synthesis in th...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید