Background: For radiotherapy of total skin including sub-cutaneous tissue up to a depth of 3 cm on the entire left leg of an adult (Angiosarcoma skin), a complex treatment with multiple stationary electron fields was planned at our clinic. The details of dosimetry, clinical dose measurements are presented. Materials and Methods: The treatment planned with 6 overlapping 9 MeV electron fields in ...

OBJECTIVES To study the long-term results of treatment of patients with generalized patch and/or plaque mycosis fungoides and to identify clinical characteristics predictive of survival and response to treatment. DESIGN A single-center, 35.5-year retrospective cohort analysis. SETTING Private referral medical center. PATIENTS One hundred seventy-six patients with generalized patch and/or ...

for superficial lesions, the electrons may be used for radiation therapy. the high energy photons and electrons are produced by a linear accelerator (linac).   many of electron fields need the shielding of normal or critical organs. the electron shields are usually lead slabs with few millimeter thickness which should be placed near the skin, less than 1 centimeter away from skin. in the inspec...

The paper focuses attention on the development of a control system for a new radiotherapy treatment machine that makes use of a betatron to deliver electron beams over the whole surface of a patient. The betatron moves above a patient at a fixed distance from the patient support system. This paper presents a method to predict the betatron trajectory, in terms of speed and position, according to...

BACKGROUND Psoriasis is a chronic inflammatory disease. In the treatment of psoriasis, cyclosporine is commonly prescribed systemic agents. However, long-term use of cyclosporine is not recommended because of side effects such as nephrotoxicity or hypertension. OBJECTIVE To ascertain the improved safety of rotational therapy using cyclosporine and methotrexate, we investigated the frequency o...

BACKGROUND Total skin electron irradiation (TSEI) is a special radiotherapy technique which has generally been used for treating adult patients with mycosis fungoides. Recently, two infants presented with leukemia cutis isolated to the skin requiring TSEI. This work discusses the commissioning and quality assurance (QA) methods for implementing a modified Stanford technique using a rotating har...

An anthropomorphic phantom was used to investigate a treatment technique and analyze the dose distributions for helical irradiation of the total skin (HITS) by helical tomotherapy (HT). Hypothetical bolus of thicknesses of 0, 10, and 15 mm was added around the phantom body to account for the dose homogeneity and setup uncertainty. A central core structure was assigned as a "complete block" to f...

Cutaneous lymphomas are particularly radiosensitive and amenable to palliative radiation therapy. Total skin electron beam therapy (TSEB) is effective for palliation of Sézary syndrome and cutaneous T-cell lymphoma with large body surface area involvement. Focal radiation therapy is often used for treatment of localized disease. Treatment of cutaneous T-cell lymphoma can often pose technical ch...

BACKGROUND Radiation therapy is performed as an adjuvant therapy when indicated following surgical resection of malignant tumors. However, radiation exposure induces acute or chronic dermatitis, depending on the radiation dose, interval, tissue volume, or irradiated area of the body. Radiation-induced skin ulcers and osteomyelitis of the underlying bone are intractable late-stage complications ...