PURPOSE Soy-based formulas are widely used as dairy substitutes to treat milk allergy patients. However, reactions to soy have been reported in a small proportion of patients with IgE-mediated milk allergies. The aim of this work was to explore whether P34, a mayor soybean allergen, is involved in this cross-reactivity. METHODS In vitro recognition of P34 was evaluated by immunoblotting, comp...

Allergy to cow's milk, egg, wheat, soy, peanut, tree nuts, fish, and shellfish constitutes the majority of food allergy reactions, but reliable estimates of their prevalence are lacking. This systematic review aimed to provide up-to-date estimates of their prevalence in Europe.Studies published in Europe from January 1, 2000, to September 30, 2012, were identified from searches of four electron...

Food protein-induced enterocolitis syndrome (FPIES) is a potentially severe non-IgE-mediated food allergy usually caused by cow's milk or soy, and more rarely by solid foods such as rice, oats, barley, chicken, turkey, egg white, green peas and peanuts. In children with FPIES, the presence of specific IgE antibodies to the causative food, either at presentation or during follow-up, defines an "...

OBJECTIVE To report two cases of infants with hemorrhagic gastritis due to cow's milk allergy. DESCRIPTION The clinical features included hematemesis, vomiting and malnutrition. All patients had eosinophilic infiltrate in gastric biopsies and got favorable clinical outcome after cow's milk free diet. COMMENTS Hemorrhagic gastritis due to cow's milk allergy is an uncommon diagnosis. Clinical...

1. Kim JS, Sinacore JM, Pongracic JA. Parental use of Epipen for children with food allergies. J Allergy Clin Immunol. 2005;116: 164–168. 2. Sicherer SH, Forman JA, Noone SA. Use assessment of selfadministered epinephrine among food-allergic children and pediatricians. Pediatrics. 2000;105:359–362. 3. Meglio P, Bartone E, Plantamura M, Arabito E, Giampietro PG. A protocol for oral desensitizati...

Turunen S, Karttunen TJ, Kokkonen J. J Pediatr. 2004; 145:606–611 Purpose of the Study. To investigate the incidence of cow’s milk allergy as evidenced by milk challenge and the findings of endoscopic and immunohistochemical examinations in children with chronic and refractory constipation. Study Population. Thirty-five children aged 3 to 15 years with recalcitrant constipation and 15 control s...

BACKGROUND AND OBJECTIVES Children with atopic dermatitis (AD) have a higher risk for development of food allergies. The objective of this study was to examine incidence of food allergy development in infants with AD and the predictive value of food-antigen-specific immunoglobulin E measurements. METHODS This trial examined the long-term safety and efficacy of pimecrolimus cream 1% in >1000 i...

BACKGROUND Limited published evidence shows oral desensitization to be a potential intervention option for cow's milk protein (CMPs) allergy. OBJECTIVE The aim of this study was to evaluate the safety and efficacy of oral desensitization in 2-year-old children with cow's milk allergy, as a treatment alternative to elimination diet. METHODS A total of 60 children aged 24-36 months with IgE-m...

but robust approach towards the identification of markers that enable the prediction of the outcome of oral immunotherapy for cow’s milk allergy. By means of ELISA, the authors determined specific IgE, IgA, IgG subclass levels against cow’s milk extract, natural single cow’s milk allergens and the egg allergen ovalbumin in 40 children with cow’s milk allergy before and after immunotherapy. Seve...

Milk processing technologies for the control of cow's milk protein allergens are reviewed in this paper. Cow's milk is a high nutritious food; however, it is also one of the most common food allergens. The major allergens from cow's milk have been found to be β-lactoglobulin, α-lactalbumin and caseins. Strategies for destroying or modifying these allergens to eliminate milk allergy are being so...