A graph is one-regular if its automorphism group acts regularly on the arc set. In this paper, we construct a new infinite family of one-regular Cayley graphs of any prescribed valency. In fact, for any two positive integers , k 2 except for ( , k) ∈ {(2,3), (2,4)}, the Cayley graph Cay(Dn,S) on dihedral groups Dn = 〈a, b | an = b2 = (ab)2 = 1〉 with S = {a1+ +···+ t b | 0 t k − 1} and n = ∑k−1 ...