نتایج جستجو برای: s typhi

تعداد نتایج: 713927  

Journal: :Infection and immunity 1987
L S Baron D J Kopecko S B Formal R Seid P Guerry C Powell

For protection against dysentery caused by Shigella flexneri 2a, an in vivo-constructed recombinant plasmid with genes specifying the S. flexneri type and group antigens located near the pro (min 6) and his (min 44) chromosomal markers, respectively, was made and transferred to the galE Salmonella typhi strain Ty21a. Strain Ty21a carrying this recombinant plasmid was shown by immunological and ...

2015
Ravichantar Nithya Siti Aminah Ahmed Chee-Hock Hoe Subash C. B. Gopinath Marimuthu Citartan Suresh V. Chinni Li Pin Lee Timofey S. Rozhdestvensky Thean-Hock Tang

Salmonellosis, a communicable disease caused by members of the Salmonella species, transmitted to humans through contaminated food or water. It is of paramount importance, to generate accurate detection methods for discriminating the various Salmonella species that cause severe infection in humans, including S. Typhi and S. Paratyphi A. Here, we formulated a strategy of detection and differenti...

2013
Richelle C. Charles Tania Sultana Mohammad Murshid Alam Yanan Yu Ying Wu-Freeman Meagan Kelly Bufano Sean M. Rollins Lillian Tsai Jason B. Harris Regina C. LaRocque Daniel T. Leung W. Abdullah Brooks Tran Vu Thieu Nga Sabina Dongol Buddha Basnyat Stephen B. Calderwood Jeremy Farrar Farhana Khanam John S. Gunn Firdausi Qadri Stephen Baker Edward T. Ryan

BACKGROUND Salmonella enterica serotype Typhi can colonize and persist in the biliary tract of infected individuals, resulting in a state of asymptomatic chronic carriage. Chronic carriers may act as persistent reservoirs of infection within a community and may introduce infection to susceptible individuals and new communities. Little is known about the interaction between the host and pathogen...

2017
Heidi Schaballie Barbara Bosch Rik Schrijvers Marijke Proesmans Kris De Boeck Mieke Nelly Boon François Vermeulen Natalie Lorent Doreen Dillaerts Glynis Frans Leen Moens Inge Derdelinckx Willy Peetermans Bjørn Kantsø Charlotte Svaerke Jørgensen Marie-Paule Emonds Xavier Bossuyt Isabelle Meyts

BACKGROUND Serotype-specific antibody responses to unconjugated pneumococcal polysaccharide vaccine (PPV) evaluated by a World Health Organization (WHO)-standardized enzyme-linked immunosorbent assay (ELISA) are the gold standard for diagnosis of specific polysaccharide antibody deficiency (SAD). The American Academy of Allergy, Asthma and Immunology (AAAAI) has proposed guidelines to interpret...

Journal: :Infection and immunity 1982
A D O'Brien

The basis for the natural resistance of mice to Salmonella typhi was examined. In contrast to Salmonella typhimurium, the virulence of S. typhi for mice was independent of the mouse strain and was not affected by inactivation of murine macrophages with silica. However, mice were more susceptible to S. typhi when given iron alone or iron and an iron chelator. The results suggest that the failure...

2010
Stephen J. Libby Michael A. Brehm Dale L. Greiner Leonard D. Shultz Michael McClelland Kelly D. Smith Brad T. Cookson Joyce E. Karlinsey Traci L. Kinkel Steffen Porwollik Rocio Canals Lisa A. Cummings Ferric C. Fang

Salmonella enterica serovar Typhi, the cause of typhoid fever, is host-adapted to humans and unable to cause disease in mice. Here, we show that S. Typhi can replicate in vivo in nonobese diabetic (NOD)-scid IL2rγ mice engrafted with human hematopoietic stem cells (hu-SRC-SCIDmice) to cause a lethal infectionwith pathological and inflammatory cytokine responses resembling human typhoid. In cont...

2006
Y. James Kang

Unlike the majority of Salmonella enterica serovars, Salmonella Typhi (S. Typhi), the etiological agent of human typhoid, is monophasic. S. Typhi normally harbours only the phase 1 flagellin gene (fliC), which encodes the H:d antigen. However, some S. Typhi strains found in Indonesia express an additional flagellin antigen termed H:z66. Molecular analysis of H:z66þ S. Typhi revealed that the H:...

Journal: :PLoS Pathogens 2007
Stephen Baker Jonathan Hardy Kenneth E Sanderson Michael Quail Ian Goodhead Robert A Kingsley Julian Parkhill Bruce Stocker Gordon Dougan

Unlike the majority of Salmonella enterica serovars, Salmonella Typhi (S. Typhi), the etiological agent of human typhoid, is monophasic. S. Typhi normally harbours only the phase 1 flagellin gene (fliC), which encodes the H:d antigen. However, some S. Typhi strains found in Indonesia express an additional flagellin antigen termed H:z66. Molecular analysis of H:z66+ S. Typhi revealed that the H:...

Journal: :Journal of clinical microbiology 2015
Rene S Hendriksen Pimlapas Leekitcharoenphon Matthew Mikoleit Jacob Dyring Jensen Rolf Sommer Kaas Louise Roer Heena B Joshi Srirat Pornruangmong Chaiwat Pulsrikarn Gladys D Gonzalez-Aviles E Ascelijn Reuland Nashwan Al Naiemi Astrid Louise Wester Frank M Aarestrup Henrik Hasman

One unreported case of extended-spectrum-beta-lactamase (ESBL)-producing Salmonella enterica serovar Typhi was identified, whole-genome sequence typed, among other analyses, and compared to other available genomes of S. Typhi. The reported strain was similar to a previously published strain harboring blaSHV-12 from the Philippines and likely part of an undetected outbreak, the first of ESBL-pro...

2013
Vanessa K. Wong Derek J. Pickard Lars Barquist Karthikeyan Sivaraman Andrew J. Page Peter J. Hart Mark J. Arends Kathryn E. Holt Leanne Kane Lynda F. Mottram Louise Ellison Ruben Bautista Chris J. McGee Sally J. Kay Thomas M. Wileman Linda J. Kenney Calman A. MacLennan Robert A. Kingsley Gordon Dougan

Proteins exhibiting hyper-variable sequences within a bacterial pathogen may be associated with host adaptation. Several lineages of the monophyletic pathogen Salmonella enterica serovar Typhi (S. Typhi) have accumulated non-synonymous mutations in the putative two-component regulatory system yehUT. Consequently we evaluated the function of yehUT in S. Typhi BRD948 and S. Typhimurium ST4/74. Tr...

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