Sepsis is a serious disease with high mortality and has been hot research topic in medical recent years. With the continuous reporting of in-depth on pathological mechanisms sepsis, various compounds have developed to prevent treat sepsis. Natural small-molecule play vital roles prevention treatment sepsis; for example, such as resveratrol, emodin, salidroside, ginsenoside, others can modulate ...

Salidroside, extracted from the root of Rhodiola rosea L, is known for its pharmacological properties, in particular its neuroprotective effects. 2-(4-Methoxyphenyl) ethyl-2-acetamido-2-deoxy-β-D-pyranoside (GlcNAc-Sal), an analog of salidroside, was recently synthesized and shown to possess neuroprotective properties. The purpose of the current study was to investigate the neuroprotective effe...

Rhodiola rosea is a genus of in the family Rosea, and top-quality medicine for strengthening tonic deficiency. Modern research has found that various pharmacological effects such as anti-fatigue, anti-oxidant, anti-aging, anti-inflammatory anti-tumor. As main active ingredient rosea, Salidroside can exert anti-tumor by inhibiting tumor cell proliferation, migration, promoting apoptosis, inducin...

A Novel Mechanism of Action for Salidroside to Alleviate Diabetic Albuminuria: Effects 1 on Albumin Transcytosis across Glomerular Endothelial Cells 2 3 Dan Wu, Xiaoyan Yang, Tao Zheng, Shasha Xing, Jianghong Wang, Jiangyang Chi, Fang 4 Bian, Wenjing Li, Gao Xu, Xiangli Bai, Guangjie Wu, Si Jin 5 6 1 Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong 7 Univer...

Abstract A rapid microwave-assisted extraction (MAE) method was established to extract commercially important salidroside from dry plant materials of Rhodiola crenulata . Several parameters such as time, solid/liquid ratio, temperature and solvent concentration were investigated for efficient extraction. The estimated maximum ratio based on parameter optimization using response surface methodol...