نتایج جستجو برای: sarcoma
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Background: Ewing's sarcoma is one of the most malignant tumors in children and young adults. Only a few established cell lines of Ewing's sarcoma have been reported, which makes it difficult to study the biological features of these tumors. We have recently established a new Ewing's sarcoma cell line designated SS-ES-1, originating from a thoracic tumor of a 16-year-old female patient. The SS-...
A miRNA-based in vivo reporter deciphers cell heterogeneity Ewing sarcoma.
Introduction/Background The recognition of uterine sarcoma allows correct therapy planning and choice surgical approach. To help to distinguish benign myoma from sarcoma, we assessed the value 6 sonographic criteria (Sarcoma Prediction Score – SPS) in a prospective cohort consecutive patients with masses. Methodology Patients planned for surgery between 2015–2019 presumed myom...
BACKGROUND Herpesvirus-like DNA sequences have recently been found in lesions from patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome (AIDS). It is not known whether these sequences are also present in classic Kaposi's sarcoma or in the Kaposi's sarcoma that occurs in homosexual men who are seronegative for the human immunodeficiency virus (HIV). METHODS We analyzed DNA...
Abstract Objective The relationship between the adolescent and young adult age groups poor overall survival in soft tissue sarcoma risk factors for outcomes patients with were analyzed. Methods medical records of 7759 Japanese diagnosed from 2006–13 accessed Bone Soft Tissue Tumor registry. epidemiological features compared those other groups. cancer rates calculated using Kaplan-Meier method. ...
Synovial sarcoma (SS) is a rare but distinctive soft tissue sarcoma (STS) that displays epithelial differentiation. It consists of 5% to 10% of STSs. Surgery is the mainstay of treatment to prevent local recurrence and maximam five-year survival rate is 40 %. Recently, SS was noted to have increased post chemotherapy survival time and the sensitivity of SS to ifosfamide-based chemotherapy h...
Prostate cancer is the most common malignant tumor in men. The vast majority of prostate tumors are represented by prostatic adenocarcinomas (up to 95%). Sarcoma a very rare adults with formidable prognosis. Early diagnosis and radical surgery offer patients best chance cure. We report case 44-year-old patient stage VI unresectable high-grade undifferentiated sarcoma, initially presenting urina...
INTRODUCTION Synovial sarcoma is a malignant soft tissue sarcoma which arises near joints. The most frequent metastasis sites of synovial sarcoma are the lungs, lymph nodes, and bone. Pancreatic metastasis is quite rare; only 3 cases have been reported worldwide to date. We herein present the 4th case of pancreatic metastasis from synovial sarcoma. METHODS AND RESULTS A 32-year-old man underw...
introduction : methotrexate (mtx) is an anti folate drug that used in malignant and non malignant patients. the usage of high dose methotrexate was limited to patients with: osteogenic sarcoma, ewing sarcoma and lymphoma. the aim this study was to determine the toxicity or side effects of very high dose methotrexate (8-10 gr/m 2 /cycle). this study is the first study in iranian patients and one...
Frequent absence of tumor suppressor FUS1 protein expression in human bone and soft tissue sarcomas.
BACKGROUND FUS1 is a tumor suppressor gene located on human chromosome 3p21.3. Frequent loss of FUS1 protein expression is associated with lung cancer development. This study examined FUS1 expression and its possible tumor-suppressive role in bone and soft tissue sarcomas. MATERIALS AND METHODS The expressions of FUS1 mRNA and FUS1 protein were assessed in sarcoma cell lines, sarcoma tissues,...
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