Purpose The detection and diagnosis of glaucoma is challenging for health professionals. In the UK, approximately 45% of patients are discharged from secondary care after one visit. Automated imaging technologies are easy to perform and could potentially be used by trained technicians as triage tests for glaucoma diagnosis. The GATE study aims to compare the diagnostic performance of three tech...

PURPOSE To evaluate the ability of scanning laser polarimetry with variable corneal compensation to detect progressive retinal nerve fiber layer (RNFL) loss in glaucoma patients and patients suspected of having the disease. METHODS This was an observational cohort study that included 335 eyes of 195 patients. Images were obtained annually with the GDx VCC scanning laser polarimeter, along wit...

PURPOSE To evaluate changes in retinal nerve fiber layer (RNFL) thickness after laser in situ keratomileusis (LASIK) using a scanning laser polarimeter with fixed corneal compensation (GDx) and the retinal thickness analyzer (RTA). METHODS Thirty-eight eyes of 19 healthy subjects (10 female and 9 male; mean age 37.0-/+8.8 years) underwent GDx and RTA measurements before and after LASIK. All s...

PURPOSE To compare the performance of scanning laser topography (SLT) and scanning laser polarimetry (SLP) on the rim of the optic nerve head and its surrounding area and thereby to evaluate whether these imaging technologies are influenced by other factors beyond the thickness of the retinal nerve fiber layer (RNFL). MATERIALS AND METHODOLOGY A total of 154 eyes from 5 different groups were ...

AIMS To compare histological thickness of the retinal nerve fibre layer in the primate with retardation measurements obtained in vivo using the Mark II Nerve Fiber Analyzer (NFA, Laser Diagnostic Technologies, San Diego, USA). METHODS Scanning laser polarimetry was performed on both eyes of a healthy anaesthetised adult primate (Macaca mulatta). The retinal nerve fibre layer thickness was mea...

PURPOSE To determine the correlations and strength of association between different imaging systems in analyzing the retinal nerve fiber layer (RNFL) of glaucoma patients: optical coherence tomography (OCT), scanning laser polarimetry (SLP) and confocal scanning laser ophthalmoscopy (CSLO). MATERIALS AND METHODOLOGY 114 eyes of patients with moderate open angle glaucoma underwent spectral dom...