Background Regional anesthesia and analgesia reduce the stress response to surgery decrease need for volatile opioids, thereby preserving cancer-specific immune defenses. This study therefore tested primary hypothesis that combining epidural anesthesia–analgesia with general improves recurrence-free survival after lung cancer surgery. Methods Adults scheduled video-assisted thoracoscopic resect...

Background: Post-operative pain for thyroid surgeries under general anaesthesia is inadequately managed. Bilateral superficial cervical plexus block (BSCPB) surgery causes adequate analgesia without any significant side effects. Dexamethasone commonly used in to prevent postoperative nausea and vomiting (PONV). The study objective was comparison of efficacy between add-on intravenously Ropivaca...

Background: The administration of bupivacaine intrathecally as a regional anesthesia is commonly used to provide for lower abdominal surgeries. motor blockage provides adequate blockage, which allows the surgeons do their work comfortably and also effective postoperative analgesia in early period. However, adding adjuvants local anesthetics prolong period after fading spinal was tried many stud...

A 71-year-old man was scheduled to undergo cardiac resynchronization therapy device (CRTD) implantation. He was combined with severe chronic heart failure due to ischemic heart disease. NYHA class was 3 to 4 and electrocardiogram showed non-sustained ventricular. Ejection fraction was about 20% revealed by transthoracic echocardiogram. He was also on several anticoagulation medications. We plan...

BACKGROUND Oral opioid formulations contribute to postoperative analgesia. In this study, we evaluated the perioperative application of oral controlled-release oxycodone to reduce postoperative IV morphine consumption and opioid side effects after lumbar discectomy. METHODS Forty patients scheduled for elective lumbar discectomy over 1 or 2 levels were included in this prospective, randomized...

BACKGROUND AND OBJECTIVES Patients undergoing abdominal surgery often receive an epidural infusion for postoperative analgesia. However, when epidural analgesia is contraindicated or unwanted, the administration of opioids is the usual means used to relieve pain. Various regional analgesia techniques used in conjunction with systemic analgesia have been reported to reduce the cumulative postope...

BACKGROUND Postoperative pain after major open gynecologic surgeries requires appropriate pain management. OBJECTIVES This study aimed at comparing perioperative patient controlled epidural analgesia (PCEA) and patient controlled intravenous analgesia (PCA) after gynecologic oncology surgeries. PATIENTS AND METHODS In this clinical trial study, 90 patients with American society of anesthesi...

Adjuncts to local anaesthetics for brachial plexus block enhances the quality and duration of analgesia. The purpose of this study was to compare two alpha-2 agonists clonidine and dexmedetomidine, when added as adjuvant to ropivacaine, in respect to onset, duration of sensory and motor block along with duration of analgesia. After informed consent, Sixty ASA I and II patients scheduled for ele...

Background: Local analgesia technique has important advantages to manage postoperative pain; however, the duration of pain relief is relatively short due to the pharmacological characteristic of local anesthetics. Hence, in the current study, we planned to explore the hypothesis that adding dexmedetomidine to levobupivacaine in transversus abdominis plane (TAP) block prolongs the duration of an...

BACKGROUND AND AIMS Various additives have been evaluated for the purpose of enhancing quality of analgesia and prolonging duration of spinal anesthesia. This randomized, double-blind study was conducted to evaluate the efficacy of intravenous dexamethasone in spinal anesthesia. METHODS A total of sixty patients scheduled for lower segment cesarean section under spinal anesthesia were randoml...