objective: although sodium valproate came to the market as an anticonvulsant drug, nowadays it's wildly used in the management of psychiatric disorders. it is used as a mood stabilizer and as an adjunctive agent in treatment of depression and psychosis. there are controversies regarding sodium valproate efficacy in psychosis. although some studies have reported that it is effective in the ...

introduction ingestion of foreign bodies has been previously reported in some patients with schizophrenia. this behavior may be a manifestation of delusional beliefs or a response to command hallucinations and can lead to severe complications. case presentation this paper reports a patient with schizophrenia who, as a manifestation of his illness, ingested a metallic skewer to kill ademon insid...

Introduction: Families who care for schizophrenia patients will experience various challenges, which are influenced by the family's knowledge and understanding of schizophrenia. This study aims to explore in their families rural Indonesia 2020.Methods: uses a qualitative research design with phenomenological approach, was conducted East Java Provincial Health Office from July October 2020. The ...

Introduction: There are several hypotheses of schizophrenia pathogenesis, including the neurodegenerative theory, which is supported by evidence for decrease neuroprotective factors’ serum levels. The proteins, that exert a protective effect on neurons and researched concerning include brain-derived neurotrophic factor (BDNF), nerve growth (NGF), neurotrophin 3 (NT3), glial cell line-derived (G...

social anxiety is a frequent, disabling condition but often unrecognized feature in schizophrenia. the aim of this study was to describe the prevalence of social anxiety among inpatients with schizophrenia. sixty inpatients with dsm-v schizophrenia were recruited from niayesh psychiatric hospital in 2015 in tehran, iran. they were interviewed with the anxiety disorders section of the scid for d...

schizophrenia is a debilitating and pervasive mental illness with devastating effects on many aspects of psychological, cognitive and social wellbeing. epidemiological and life-cycle data point to significant differences in the incidence and course of schizophrenia between men and women, suggesting that estrogen plays a “protective” role . adjunctive estrogen therapy has been shown to be effect...

introduction: the purpose of this study was to assess prevalence and possible variables on the change of diagnosis in mood disorder patients to schizophrenia. methods: this study was a retrospective and comparative analytic research that was performed in 2006 at razi psychiatric hospital. the study included all of the 176 patients who were hospitalized in 2000 with diagnosis of a mood disorder....

introduction: comorbid obsessive-compulsive disorder (ocd) has been reported among patients with schizophrenia in other countries. but, the literature is not well-documented on this issue in iran (persia). the present study aimed to investigate the prevalence and severity of ocd and some of its related factors in a group of patients with schizophrenia in iran.  methods: this is a cross-sectiona...

introduction: a number of research studies have shown that the new generation of neuroleptic medications can more effectively contribute to treating negative symptoms of schizophrenia compared with the first generation by influence cognitive functioning. the present study examined the therapeutic effectiveness of manufactured risperidone and haloperidol in iran on treating the negative symptoms...