BACKGROUND Population-based colorectal cancer screening has been shown to reduce cancer specific mortality and is used across the UK. Despite evidence that older age, male sex and deprivation are associated with an increased incidence of colorectal cancer, uptake of bowel cancer screening varies across demographic groups. The aim of this study was to assess the impact of age, sex and deprivatio...

In recent years, the role of primary care physicians (PCPs) in the diagnosis and management of gastrointestinal disorders, including screening for colorectal cancer (CRC), has been recognized as very important. The available data indicate that PCPs are not adequately following CRC screening guidelines because a number of factors have been identified as significant barriers to the proper applica...

Background Colorectal cancer is the third most common worldwide. Colonoscopy gold standard for colorectal screening. However, colonoscopy participation rate in China much lower than that Europe and United States. As only non-sedated colonoscopies are offered screening programs China, absence of sedation may contribute to this gap. Methods To explore effect free partially participant-paid sedate...

Background and AimsScreening for colorectal cancer (CRC) can effectively reduce CRC incidence mortality. Besides colonoscopy, tests the detection of biomarkers in stool, blood, or serum, including fecal immunochemical test (FIT), ColoGuard, Epi proColon, PolypDx, have recently been advanced. We aimed to identify characteristics theoretic, highly efficient screening calculated effectiveness cost...

Colonoscopy is an important screening and therapeutic modality for colorectal cancer. Unlike other screening tests, colonoscopy is dependent on pre-procedure bowel preparation. If the bowel preparation is poor, significant pathology may be missed. Many factors are known to improve bowel preparation. This review will highlight those factors that may optimize the bowel preparation, including choi...

BACKGROUND Colorectal cancer (CRC) is the second most prevalent type of cancer in Europe. Early detection and removal of CRC or its precursor lesions by population screening can reduce mortality. Colonoscopy and computed tomography colonography (CT colonography) are highly accurate exams and screening options that examine the entire colon. The success of screening depends on the participation r...

We evaluated whether age- and gender-based colorectal cancer screening is cost-effective.Recent studies in the United States identified age and gender as 2 important variables predicting advanced proximal neoplasia, and that women aged <60 to 70 years were more suited for sigmoidoscopy screening due to their low risk of proximal neoplasia. Yet, quantitative assessment of the incremental benefit...

BACKGROUND The U.S. Preventive Services Task Force recommends against routine screening for colorectal cancer (CRC) in adequately screened persons older than 75 years but does not address the appropriateness of screening in elderly persons without previous screening. OBJECTIVE To determine at what ages CRC screening should be considered in unscreened elderly persons and to determine which tes...

ObjectiveTo estimate the cost-effectiveness of multitarget stool DNA testing (MT-sDNA) compared with colonoscopy and fecal immunochemical (FIT) for Alaska Native adults.Patients MethodsA Markov model was used to evaluate 3 screening test effects over 40 years. Outcomes included colorectal cancer (CRC) incidence mortality, costs, quality-adjusted life-years (QALYs), incremental ratios (ICERs). T...

Colorectal cancer (CRC) is a common cancer worldwide. The incidence and mortality rates of CRC are higher among lower socioeconomic status (SES) populations. We investigated the association between different indicators of SES and CRC screening rates in Korea. The eligible study population included males and females aged 50 to 74 years who participated in a nationwide cross-sectional survey (201...