Two cases of scrub typhus are described. In both, the existence of a genital eschar with regional adenitis pointed to venereal infection. Although only two cases have been recorded during the previous two years at the Venereal Disease Department of the British Military Hospital, Singapore, it is possible that others have been missed and it is considered that scrub typhus should enter into the d...

Scrub typhus is not one of the more commonly encountered diseases in travelers returning from Asia, but it deserves more consideration in view of its severity and the availability of specific chemotherapy and chemoprophylaxis. We describe a case of scrub typhus that was associated with coma and multiorgan failure in a traveler returning to the United States from Thailand. The diagnosis was made...

Weil-Felix reaction with blood of patients suffering ̂ from scrub typhus during its course shows significant agglutination titres against yproteus XK strains. In Bombay. Patel (1940) reported on two cases but the titres were ^r below the diagnostic level. Later, two more cases clinically suspected and serologically confirmed were reported by Patel (1943) and Patel (1943). Systematic Weil-Felix r...

OBJECTIVE This study analyzes the spatial distribution of scrub typhus in Korea. METHODS A spatial distribution of Orientia tsutsugamushi occurrence using a geographic information system (GIS) is presented, and analyzed by means of spatial clustering and correlations. RESULTS The provinces of Gangwon-do and Gyeongsangbuk-do show a low incidence throughout the year. Some districts have almos...

Orientia tsutsugamushi induces vasculitis leading to symptoms of systemic organ invasion including meningitis and meningoencephalitis. We conducted a retrospective case-control study of scrub typhus patients to investigate the clinical and laboratory features of patients with scrub typhus meningitis or meningoencephalitis, and the therapeutic outcomes, and to determine the predictor factors. Ca...

Background. Scrub typhus may be a life-threatening infection that usually presents as acute undifferentiated febrile illness (AUFI). Because of the similarity of clinical features and absence of sensitive point-of-care testing, however, clinicians have difficulty in differentiating scrub typhus from other etiologies among patients presenting with AUFI in acute healthcare settings. Methods. This...

BACKGROUND Infection-related acute kidney injury (AKI) is an important preventable cause of morbidity and mortality in the tropical region. The prevalence and outcome of kidney involvement, especially AKI, in scrub typhus is not known. We investigated all patients with undiagnosed fever and multisystem involvement for scrub typhus and present the pattern of renal involvement seen. METHODS Fro...

Dengue fever and scrub typhus are common causes of acute febrile illness of unclear origin in Asia. Though coinfections of many vector-borne diseases have been described, articles on dengue and scrub typhus coinfection are distinctly limited. In case of coinfection with dengue and scrub typhus, vigilant monitoring of vitals, platelets transfusion, and timely treatment with doxycycline are neces...

Scrub typhus is the most important rickettsial disease in the world. Its previous endemic region was considered to be in Asia, Australia and islands in the Indian and Pacific Oceans; this area was referred to as the Tsutsugamushi Triangle. Accumulation of serological, molecular, genetic, and culture data have shown that not only is scrub typhus not limited to the Tsutsugamushi Triangle, but can...

OBJECTIVE This retrospective study investigated abnormal hepatic dysfunction and abdominal computed tomography (CT) findings in scrub typhus. METHODS Three hundred forty nine adult patients were diagnosed with scrub typhus. Ninety four underwent abdominal CT. The CT images were reviewed by the attending radiologist. Patient data of history, symptoms, signs, and results of laboratory tests wer...