BACKGROUND Despite the mounting importance of granulocytapheresis (GCAP) for inflammatory bowel disease (IBD) treatment, its effectiveness in steroid-dependent (SD) and steroid-resistant (SR) patients has not been clearly evaluated. This prospective observational study describes the use of GCAP in SD and SR patients with either Ulcerative Colitis (UC) or Crohn's Disease (CD). METHODS 118 pati...

The authors prospectively examined whether change in dietary glycemic index (GI), glycemic load (GL), fiber intake, or whole-grain intake during puberty is associated with concurrent change in percentage of body fat (%BF) or body mass index (BMI; weight (kg)/height)(2). Linear mixed-effects regression analyses were performed in 215 participants from the Dortmund Nutritional and Anthropometric L...

BACKGROUND AND OBJECTIVES Ambulatory arterial stiffness index (AASI) is well known as a predictor of cardiovascular mortality in hypertensive patients. Mathematically, AASI reflect the standard deviation (SD) of blood pressure (BP) variation. AASI is measured higher levels in non-dipper than dipper. Thus, AASI has a possibility of not only reflecting arterial stiffness but also BP variability a...

INTRODUCTION To assess the comparative effectiveness of febuxostat and allopurinol in reducing serum urate (sUA) levels in a real-world U.S. managed care setting. METHODS This retrospective study utilized 2009 to 2012 medical and pharmacy claims and laboratory data from a large U.S. commercial and Medicare Advantage health plan. Study patients had at least one medical claim with a diagnosis o...

Blood glucose variability is known to be associated with increased risk of long-term complications. Reliable indices for predicting hyperglycaemic and hypoglycaemic fluctuations are therefore needed. Glycaemic standard deviation (SD) obtained by continuous glucose monitoring correlates closely with nine previously described glycaemic variability formulas. Here, new indices predictive of glycaem...

Background. There is a need in primary care for simple asthma outcome measures that are valid in terms of their relationship with lung function and capable of predicting those patients for whom additional management is indicated. Aim. To assess the predictive validity of a revised asthma morbidity index in United Kingdom (UK) general practice. Method. Morbidity index and peak flow rate data wer...

Objective: Seborrheic dermatitis (SD) is a common, chronic, recurring, inflammatory skin disorder. The cause of the disease still completely unknown. Recent studies suggest that Demodex parasites may play role in etiopathogenesis SD. purpose this study was, to investigate presence SD and its association with severity. Material Methods: A total 40 patients over age 18 years, who were clinically ...

UNLABELLED Diabetic polyneuropathy can be confirmed by nerve conduction studies. The data can be analyzed in the form of a combined index instead of individual parameters. METHODS The combined index included five parameters of nerve conduction studies commonly used for evaluation of polyneuropathies. We evaluated sensitivity in 100 diabetic patients with suspected polyneuropathy, and specific...

To evaluate significant caries (SiC) index values and related factors in Turkish children aged 5-6 years old, children from 5 nursery schools in Istanbul were included in a cross-sectional study. Sociodemographic information and data about oral care habits were obtained from the records and from parents. Of 542 students examined, the mean decayed/missing/filled primary teeth (dmft) index was 3....