نتایج جستجو برای: second line therapy
تعداد نتایج: 1585160 فیلتر نتایج به سال:
OBJECTIVE The objective of this study was to assess the efficacy, safety and tolerability of vonoprazan, a novel potassium-competitive acid blocker, as a component of Helicobacter pylori eradication therapy. DESIGN A randomised, double-blind, multicentre, parallel-group study was conducted to verify the non-inferiority of vonoprazan 20 mg to lansoprazole 30 mg as part of first-line triple the...
Since the era of tyrosine kinase inhibitor (TKI) therapy, there has been an increase in median survival chronic myeloid leukemia. Nevertheless, nowadays were several cases leukemia that are resistant to first-line TKIs, so second-line TKIs introduced. Assessment therapeutic response was performed using a complete peripheral blood examination, bone marrow aspiration cytogenetic and quantitative ...
Methods Study was conducted in ART centre, IMS, BHU. Patients who failed on first line ART (NACO criteria) were included in the study after consent. Virological, immunological and clinical response was assessed at 24 weeks. Independent t-test /Mann-Whitney U test was used for making comparison among the independent groups. Chi-square test was used to test the association between categorical var...
After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression. We conducted a systematic review of the literature for the activity, effectiveness and toxicity of second line treatment. The results are presented according to the class of drugs: chemotherap...
BACKGROUND Patients with advanced urothelial carcinoma that progresses after platinum-based chemotherapy have a poor prognosis and limited treatment options. METHODS In this open-label, international, phase 3 trial, we randomly assigned 542 patients with advanced urothelial cancer that recurred or progressed after platinum-based chemotherapy to receive pembrolizumab (a highly selective, human...
(VEGF) levels in our study. The lowest and highest levels that we observed were 202 pg/mL and 1,538 pg/mL, respectively. We have five patients with VEGF levels 1,000 pg/mL. All of these patients have bilateral infiltration in their chest radiographs. A significant correlation (p 0.05) was observed between VEGF levels and fever in active pulmonary tuberculosis patients. However, there was not an...
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