traumatic brain injury (tbi) is a global health concern that typically causes emotional disturbances and cognitive dysfunction. it elicits a complex secondary injury response, with neuroinflammation as a crucial central component. secondary pathologies following tbi may be associated with chronic neurodegenerative disorders and an enhanced likelihood of developing dementia-like disease in later...

spinal cord injury (sci) actuate to complex cellular and molecular interactions within the central nervous system in a heave to repair the initial tissue damage. the pathophysiology of acute spinal cord injury (sci) involves primary and secondary mechanisms. neuroinflammation is an important secondary injury process in sci. the local inflammatory microenvironment within the injured spinal cord ...

at first, in order to define acute toxicity of diazinon insecticide and butachlor herbicide, acute toxicity tests (lc5096h) were done, based on standard method (1989) o.e.c.d. in static way and for 96 hours. and the amount of acute toxicity (lc5096h) of diazinon and butachlor in 1 to 2 gram vimba vimba persa fry larva was determined to be 0.09 and 0.61 respectively. in order to do histology stu...

Children with acute lymphocytic leukemia, who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate, were randomized into three groups receiving (1) no further therapy, (2) BCG, and (3) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine. Children continuing in remission after 8 mo on chemotherapy in group 3 ...

aim : we investigated whether the level of il8 was different in patients with chronic and acute toxoplasma gondii infection during the pregnancy compared with control group. background : it is well established that t.gondii infection induces a strong cell-mediated immune response. patients and methods : elisa was used to determine the level of il8 in sera of 568 pregnant women. patients were di...

abstract most pheochromocytomas are not suspected clinically while a high percentage of them are curable with surgery. we present the case of an adult cocaine-addicted male patient with an underlying pheochromocytoma and repeated myocardial infarctions. computed tomography showed a left round adrenal mass, also high 24-hour urine levels of catecholamines and metanephrines were detected from uri...

how to cite this article: talebian a, goudarzi rm, mohammadzadeh m , mirzadeh as. vincristine-induced cranial neuropathy. iran j child neurol. 2014 winter; 8(1):66-68.   abstract vincristine (vcr) is a vinca alkaloid that is used for treatment of many malignancies. the vinca alkaloids are neurotoxic, usually causing a peripheral neuropathy, but cranial neuropathies are rare as side effects.  de...

background: restless legs  syndrome  (rls)  is the  most common movement disorder in pregnancy, which can be idiopathic  or secondary. there are  limited  comparative data  regarding  these  two forms of rls.  the aim of this study was to compare  clinical features  of idiopathic  and secondary rls in pregnant women. methods: over a period  of 3 months, 443 women  who admitted for delivery in t...