Characteristic sex differences in mating strategies (e.g., choosy females, unselective males) have been claimed by Trivers and other theorists to evolve as an automatic consequence of sex differences in minimum parental investment, arising chiefly from greater female reproductive refractoriness. The theory has been supported by correlational evidence and conceptual analogies to economics. A sim...

abstract background: molecular imprinting is a method for synthesizing polymers with structure-selective adsorption properties with applications such as, selectivity binding, drug delivery systems and anti-bodies. the present study aims at optimizing the preparation of molecularly imprinted polymer (mip) against l-phenylalanine, in order to increase phenylalanine-binding in enzymatic intestinal...

Songbirds such as the white-crowned sparrow memorize the song of conspecific adults during a critical period early in life and later in life develop song by utilizing auditory feedback. Neurons in one of the telencephalic nuclei controlling song have recently been shown to respond to acoustic stimuli. I investigated the auditory response properties of units in this nucleus using a technique tha...

Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rate of incidence of the two kinds of signal, and to determine how they combine, ...

In this article the effects of process parameters of CHF31N2 plasma etching chemistry ~rf power 50–70 W, pressure 22.5–52.5 mTorr, and N2 content 0%–95%! and mask materials ~photoresist, aluminum, and silicon nitride! on the etching selectivity of silicon nitride over polysilicon are investigated. It was found that the selectivity increased with the N2 content in the range of 0%–85% and then de...

Elmsjö, A. 2017. Selectivity in NMR and LC-MS Metabolomics. The Importance of Sample Preparation and Separation, and how to Measure Selectivity in LC-MS Metabolomics. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 232. 40 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9879-5. Until now, most metabolomics protocols have been optimized towards ...

Neurons in sensory cortex show stimulus selectivity and sparse population response, even in cases where no strong functionally specific structure in connectivity can be detected. This raises the question whether selectivity and sparseness can be generated and maintained in randomly connected networks. We consider a recurrent network of excitatory and inhibitory spiking neurons with random conne...

BACKGROUND Fifteen 3-styrylchromones were subjected to quantitative structure-activity relationship (QSAR) analysis based on their cytotoxicity, tumor selectivity and anti-HIV activity, in order to explore their biological activities. MATERIALS AND METHODS Cytotoxicity against four human oral squamous cell carcinoma (OSCC) cell lines and three human oral normal cells was determined by the 3-(...

The discovery of new anti-infective compounds is stagnating and multi-resistant bacteria continue to emerge, threatening to end the "antibiotic era". Antimicrobial peptides (AMPs) and lipo-peptides such as daptomycin offer themselves as a new potential class of antibiotics; however, further optimization is needed if AMPs are to find broad use as antibiotics. In the present work, eight analogues...