Acyclovir, a BCS class III drug, has high ability to fight the herpes virus but low permeability and is poorly soluble in water. In order obtain expected effect of viral infection on skin, penetration active ingredients becomes critical factor for topical treatment achieve desired concentration. This study was see adding isopropyl myristate propylene glycol as enhancers that help diffuse drug t...

UNLABELLED BACKGROUND Evolution has selected for organisms that benefit from genetically encoded cell-cell communication. Engineers have begun to repurpose elements of natural communication systems to realize programmed pattern formation and coordinate other population-level behaviors. However, existing engineered systems rely on system-specific small molecules to send molecular messages amo...

In recent years, the dynamic aspects of oral perception food have increasingly been taken into account in texture characterization. At same time, experimental settings instrumental measurements also emulating “oral contexts” more closely. The related to in-mouth handling that incorporated studies include using saliva as a key material. Semisolid (or liquid) does not usually need mastication but...

Free-living diazotrophs are diverse and ubiquitous in soil, contributing the nitrogen pool in natural ecosystems. The isolation of nitrogen-fixing microorganisms has relied on semisolid nitrogen-free medium enrichment, followed by multiple subculturing steps. These procedures limit the diversity of recovered isolates. In the current study, we investigated three different isolation strategies fo...

The 3D printing thixo-forming process is a method that utilizes semisolid thixotropic feedstock for layer extrusion by controlling viscosity below the complete melting temperature of metallic alloys to form structure. producing has significant impact on alloy microstructure, which critical material’s printability. This study aims propose heat treatment processing window Pb-40% Sn use as billets...

In this systematic study, we attempt to thoroughly understand the aggregation mechanism of conductive carbon black in aqueous dispersing medium and optimize formulation suspension electrodes for sodium–ion semisolid flow battery applications. For first time, present branched micelle solution as an electrolyte that introduces widest electrochemical stability window 3.5 V, from –3 + 0.5 V vs. Ag/...

Analytical method validation ensures that a provides trustworthy information about particular sample when applied in accordance with the predefined protocol. According to regulatory standards, rheological characteristics of topically semisolid formulations are one key elements involved microstructure equivalence documentation. Therefore, for generic drug product manufacturers, it is dire need t...