Stimulus information and cognitive states of an animal are represented by correlated population activity neurons. The maximum entropy method provides a principled way to describe the using much less parameters than number possible patterns. This successfully explained stationary spiking neural populations such as in vitro retinal ganglion cells. Modeling cortical circuitries vivo, however, has ...

Many types of sensory neurons contain modified cilia where sensory signal transduction occurs. We report that the C. elegans gene daf-19 encodes an RFX-type transcription factor that is expressed specifically in all ciliated sensory neurons. Loss of daf-19 function causes the absence of cilia, resulting in severe sensory defects. Several genes that function in all ciliated sensory neurons have ...

Intrinsic neuronal and circuit properties control the responses of large ensembles of neurons by creating spatiotemporal patterns of activity that are used for sensory processing, memory formation, and other cognitive tasks. The modeling of such systems requires computationally efficient single-neuron models capable of displaying realistic response properties. We developed a set of reduced mode...