Flow cytometry can be used to detect antibody that kills Borrelia burgdorferi. Borreliacidal activity was detected within 3 h of incubating B. burgdorferi with immune serum and complement. Right-angle light scatter and propidium iodide fluorescence were the cytometric parameters which correlated best with in vitro killing of B. burgdorferi. Flow cytometry is a rapid method for determining the p...

Sir, Mycobacteria are known to have several immunologically active antigenic components like 38 Kd antigen, 30 Kd antigen, 16 Kd antigen, A60 antigen and lipoarabinomannan (LAM). 1 The MycoDot test is a new simple, rapid (20 minutes) and reliable serodiagnostic technique that can detect antimycobacterial antibodies in the serum or blood. It offers a low cost, single visit aid in the diagnosis o...

The genus Anaplasma (Rickettsiales: Anaplasmataceae) includes several pathogens of veterinary and human medical importance. An understanding of the diversity of Anaplasma major surface proteins (MSPs), including those MSPs that modulate infection, development of persistent infections, and transmission of pathogens by ticks, is derived in part, by characterization and phylogenetic analyses of ge...