نتایج جستجو برای: serum biomarkers

تعداد نتایج: 392736  

Journal: :Clinical Cancer Investigation Journal 2014

2015
Angera H Kuo Marek Ancukiewicz Kevin R Kozak Torunn I Yock Timothy P Padera

BACKGROUND Thoracic and cardiac irradiation increases the risk of pulmonary and cardiovascular disease. In addition, radiation, often in combination with chemotherapy, can cause treatment-related pneumonitis. Previously, we showed that the common marker for cardiac damage, troponin T, was not elevated by chemoradiation [Lung Cancer 62:351-355, 2008]. In this study, we explore whether dose-volum...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2011
Sakkadech Limmahakhun Peraphan Pothacharoen Nipon Theera-Umpon Olarn Arpornchayanon Taninnit Leerapun Sirichai Luevitoonvechkij Dumnoensun Pruksakorn

BACKGROUND Currently, serum biomarkers play an important role as sensitive tools for monitoring the cancer development and progression. Each biomarker represents a specific pathogenesis and has different predictive capability. In order to identify their characteristics in human osteosarcoma, multiple potential biomarkers were analyzed simultaneously with clinical presentations. MATERIALS AND ...

Journal: :Clinical chemistry 2012
Steinar Hustad Simone Eussen Øivind Midttun Arve Ulvik Puck M van de Kant Lars Mørkrid Randi Gislefoss Per M Ueland

BACKGROUND Biomarkers and metabolites related to B vitamin function and one-carbon metabolism have been studied as predictors of chronic diseases in studies based on samples stored in biobanks. For most biomarkers, stability data are lacking or fragmentary. METHODS Degradation and accumulation kinetics of 32 biomarkers were determined at 23 °C in serum and plasma (EDTA, heparin, and citrate) ...

Journal: :Archivos de bronconeumologia 2014
Patricia Lloberes Sara Sánchez-Vidaurre Àlex Ferré María Jesús Cruz Juan Lorente Gabriel Sampol Ferran Morell Xavier Muñoz

INTRODUCTION Studies on inflammation biomarkers in serum and in exhaled breath condensate (EBC) in obstructive sleep apnea (OSA) have shown conflicting results. The objective of this study is to assess EBC and serum biomarkers in OSA patients at baseline and after continuous positive airway pressure (CPAP) or upper airway surgery (UAS). PATIENTS AND METHODS Nine OSA patients referred for UAS ...

2016
Ayumi Nishikawa Katsuya Suzuki Yoshiaki Kassai Yuumi Gotou Maiko Takiguchi Takahiro Miyazaki Keiko Yoshimoto Hidekata Yasuoka Kunihiro Yamaoka Rimpei Morita Akihiko Yoshimura Tsutomu Takeuchi

BACKGROUND In this study, we sought to identify definitive biomarkers associated with disease activity in primary Sjögren's syndrome (pSS). METHODS Serum protein concentrations in pSS patients and healthy controls (HCs) were comprehensively screened using high-throughput proteomic analysis, and differentially expressed proteins were extracted. Correlation between differentially expressed prot...

ژورنال: دانشور پزشکی 2010
جلائی, شهره , زارع, مرجان , غضنفری, طوبی , فقیه‌زاده, سقراط ,

Background and Objective: Here,it is tried to assess an insight behind using IFN-G,IL-2,IL-4,and IL-10 biomarkers as potential surrogate endpoints for skin diseases caused by exposure to mustard gas. Potentially,a biomarker is a valid surrogate if assessment of the treatment effect based on surrogate endpoint leads to the same result based on true clinical endpoint.  Materials and Methods: In S...

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